REGIMENS/TREATMENT SWITCHING STRATEGIES IN ANTIRETROVIRAL NAIVE CHILDREN ACTG390

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 ACTG 390本研究将评估两种不同的抗HIV药物治疗组合，并将使用两种方案中的一种从一种治疗组合转换为另一种治疗组合。其中一个计划将在血液中的HIV数量（病毒载量）为1，000拷贝时转换治疗组合，另一个计划将在血液中的HIV数量为30，000拷贝时转换治疗。该研究将评估在四年的治疗中，两种转换计划中的任何一种的获益是否存在差异。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. ACTG390This study will evaluate two different treatment combinations of anti-HIV drugs and will use one of two plans for switching from one to the other treatment combinations. One plan will switch treatment combination when the amount of HIV in the bloodstream (viral load) is 1,000 copies and the other plan will switch treatment when the amount of HIV in the bloodstream is 30,000 copies. The study will evaluate if there is a difference in benefit for either of the two switching plans in a four year treatment.