HAART REGIMENS IN HIV ADOLESCENTS PACT 1034

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 这项研究将比较两种不同的抗艾滋病毒药物治疗组合在儿童体内的效果。这些抗HIV药物组合已被食品和药物管理局（FDA）批准，但更高剂量的洛匹那韦/利托那韦（Kaletra）和依法韦仑（Sustiva）是实验性的。这两种组合已被证明是有效的，在减少血液中的艾滋病毒的量。此外，研究将确定是否应针对个体受试者调整某些药物的剂量。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study will compare how well two different treatment combinations of anti-HIV drugs will work in a child's body. These anti-HIV drug combinations have been approved by the FOod and Drug Administration(FDA) , however the higher doses of lopinavir/ritonavir (Kaletra) and efavirenz (Sustiva) are experimental. Both combinations have shown to be effective in decreasing the amount of HIV in the bloodstream. In addition, the study will determine if the dose of some medications should be adjusted for individual subjects.