UPPER AIRWAY MUSCLE ACTIVITY AND LUNG VOLUME DURING STABLE AND PERIODIC BREATHIN

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本研究的具体目的是确定OSA患者在稳定睡眠/呼吸期间和周期性呼吸期间的上气道肌肉活动或肺容量是否不同。 假设上气道扩张肌活动和/或呼气末肺容量的差异有助于OSA患者睡眠阶段内和睡眠阶段之间呼吸暂停严重程度的变异性。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The specific aim of this study is to determine whether upper airway muscle activity or lung volume differs between periods of stable sleep/breathing and periods of cyclical breathing in OSA patients. The hypothesis is that differences in upper airway dilator muscle activity and/or end expiratory lung volume contribute to the variability of apnea severity within and between sleep stages in a given patient with OSA.