Socioeconomic Status and Post-Injury Quality of Life and Functional Ability

描述(由申请人提供)：这项K23奖项将允许候选人获得必要的培训和技能，以发展和领导以患者为中心的研究项目，研究领域的生活质量和受伤后的功能结果。职业发展计划的目标是使候选人获得核心知识，在研究方法、数据管理和解释方面获得进一步的专业知识，并加强其科学写作和学术领导技能。为了实现职业发展目标，应聘者将拥有一个跨学科的导师团队，将有深入的教学经验，将开展有指导的研究项目，并将在其感兴趣的领域制定未来的研究方案。候选人的指导研究计划将利用田纳西大学健康科学中心的资源和候选人的导师(唐娜·海瑟薇博士、安德鲁·布什博士和蒂莫西·法比安医学博士)的指导来实现该项目的具体目标。具体目的是：(1)确定伤前社会经济状况与中、重度创伤后功能能力的关系；(2)调查伤前社会经济状况与中、重度伤后生活质量的关系。为了实现这些目标，田纳西州孟菲斯方圆150英里范围内唯一的I级创伤中心收治了250名中到重度伤者，将对其进行为期一年的跟踪调查。有关参与者的个人水平、社会经济地位和受伤前的生活质量和功能能力的详细信息将在尽可能接近入院时获得。参与者所居住的特定人口普查地区组将使用地理编码来确定。根据这一信息，将根据人口普查数据确定具体的社区一级社会经济指标。在随访期内，将进行功能能力和生活质量的测定。受伤前个人和邻里层面的社会经济状况与受伤后的功能能力和生活质量之间的关系将使用分层线性模型来确定。由于每年有2800多万来自各行各业的美国人受到伤害，因此了解社会经济状况如何影响受伤后的康复至关重要。一旦了解了这种关系，就可以设计干预措施，以确保来自各行各业的受伤人员在受伤后达到可能的最高水平的功能能力和生活质量。

DESCRIPTION (provided by applicant): This K23 award will allow the candidate to obtain the training and skills necessary to develop and lead patient-oriented research projects in the field of quality of life and functional outcomes after injury. The aims of the career development plan are for the candidate to acquire core knowledge, to gain further expertise in research methodology, data management and interpretation, and to strengthen his scientific writing, and academic leadership skills. To achieve the career development aims, the candidate will have an interdisciplinary mentor team, will have an in-depth didactic experience, will carry out a mentored research project and will develop future research protocols in his area of interest. The candidate's mentored research plan will utilize the resources of the University of Tennessee Health Science Center and guidance of the candidate's mentors (Donna Hathaway, PhD, Andrew Bush, PhD, and Timothy Fabian, MD) to achieve the specific aims of the project. The specific aims are: (1) To determine the relationship between pre-injury socioeconomic status and functional ability following moderate to severe injury; (2) To investigate the association between pre-injury socioeconomic status and quality of life following moderate to severe injury. To address these aims 250 moderately to severely injured persons admitted to the only Level I Trauma Center for a 150-mile radius to Memphis, Tennessee will be followed for one year. Detailed information regarding participants' individual level socioeconomic status and pre-injury quality of life and functional ability will be obtained as close to the time of admission as possible. The specific census tract group in which the participant lives will be determined using geocoding. From this information specific neighborhood level socioeconomic indicators will be determined from Census Data. Over the follow-up period, determinations of functional ability and quality of life will be made. The relationship between pre-injury socioeconomic status on the individual and neighborhood level and post-injury functional ability and quality of life will be determined using hierarchical linear modeling. Because injury touches over 28 million Americans a year from all walks of life, understanding how socioeconomic status influences recovery after injury is critical. Once this relationship is understood, interventions can be designed to ensure that injured people from all walks of life will achieve the highest levels of functional ability and quality of life possible after injury.