SOUTH TEXAS PARENT DIABETES PREVENTION TRAIL (STPDPT)

拟议的墨西哥裔美国人糖尿病英才中心旨在开展 墨西哥裔美国人糖尿病及其并发症的生理学进展研究， 并制定糖尿病预防策略和测试有效干预的创新方法 受2型糖尿病严重影响的少数民族人群。该中心提出了一个行政核心，一个 研究核心，包括三个研究项目和两个试点研究、一个培训核心和一个社区 接洽核心。 作为研究核心的一部分，南得克萨斯州父母糖尿病预防试验(STPDPT)旨在测试 针对父母的简短动机强化访谈(MEI)治疗的有效性 这样他们的孩子就会：a)减少看屏幕的时间或久坐不动的时间 行为；b)减少高卡路里、低营养食物的消费；c)增加身体健康水平 活动。这些目标将通过将360名儿童随机分配到以下两种治疗条件之一来实现：a) The en Vivo！基于电话和互联网的梅家长治疗方案；以及b)无治疗控制。我们 将检查选定的饮食、久坐和体力活动行为的积极变化是否会导致 减少体重增加和与2型糖尿病相关的危险因素。拟议的项目将影响：a) 体重指数(BMI)，b)C反应蛋白(CRP)，c)胰岛素抵抗，d)HbA1c，以及e)行为 以及这些生理指标的心理社会前兆。家庭将被随机分配到STPDPT 治疗组接受6~9次梅电话治疗，并进行随访 在12个月的时间里，通过互联网、时事通讯和漫画书联系。研究目的：1)开展 与家长、老师和学生的访谈，以确定梅电话和互联网的总体可行性 家长糖尿病预防策略(2007年秋季)；2)在#年对200名家长进行横断面调查 南得克萨斯州下里奥格兰德河谷扩展和确认AIM 1的调查结果(2008年春季)；3)至 使用试点数据为家长量身定制基于MEI的家长计划(2008年夏季)；4)评估影响 基于MEI的父母程序对9-14岁儿童生理和行为结果的随机研究 从卡梅伦家族成员招募的360个家庭(父母/孩子二人)的临床试验方法 县西班牙裔队列(2008-2011年秋季)。

The proposed Center of Excellence on Diabetes in Americans of Mexican Descent aims to conduct research on the physiologic progression to diabetes and its complications among Mexican Americans, and to develop diabetes prevention strategies and test innovative approaches to effective interventions in a minority population severely affected by type 2 diabetes. This Center proposes an administrative core, a research core including three research projects and two pilot studies, a training core and a community engagement core. As part of the research core, the South Texas Parent Diabetes Prevention Trial (STPDPT) aims to test the effectiveness of a brief motivational enhanced interview (MEI) treatment aimed at parents to modify the home environment so that their children will: a) reduce "screen time" or hours engaged in sedentary behaviors; b) reduce consumption of high calorie, low nutrient foods; and c) increase levels of physical activity. These aims will be accomplished by randomizing 360 children to one of two treatment conditions: a) the En Vivo! MEI telephone and Internet based parent treatment program; and b) no-treatment control. We will examine if positive changes in selected dietary, sedentary and physical activity behaviors result in decreased weight gain and risk factors associated with type 2 diabetes. The proposed project will impact: a) body mass index (BMI), b) C-reactive protein (CRP), c) insulin resistance, d) HbA1c, as well e) behavioral and psychosocial precursors to these physical measures. Families will be randomized to the STPDPT condition or a comparison group; those in the treatment group will receive 6-9 MEI phone calls plus follow-up contact via the Internet and newsletters and comic books over a 12 month period. Study Aims: 1) To conduct interviews with parents, teachers, and students to determine overall feasibility of MEI telephone and Internet parent diabetes prevention strategies (Fall, 2007); 2) To conduct a cross sectional survey of 200 parents in the South Texas Lower Rio Grande Valley to extend and confirm findings from Aim 1 (Spring, 2008); 3) To use pilot data to tailor the MEI based parent program for parents (Summer 2008); 4) To assess the impact MEI based parent program on physiologic and behavioral outcomes on children aged 9-14 using randomized clinical trial methodology with 360 families (parent/child dyad) recruited from members of the Cameron County Hispanic Cohort (Fall 2008 - 2011).