SOUTH TEXAS PARENT DIABETES PREVENTION TRAIL (STPDPT)

拟议的墨西哥裔美国人糖尿病卓越中心旨在开展 对墨西哥裔美国人糖尿病及其并发症的生理进展的研究， 制定糖尿病预防策略并测试有效干预措施的创新方法 受 2 型糖尿病严重影响的少数群体。该中心提出了一个行政核心、一个 研究核心包括三个研究项目和两项试点研究、一个培训核心和一个社区 参与核心。 作为研究核心的一部分，南德克萨斯家长糖尿病预防试验 (STPDPT) 旨在测试 简短的动机强化访谈（MEI）治疗的有效性，旨在让家长改变 家庭环境，使他们的孩子能够：a）减少“屏幕时间”或久坐的时间 行为； b) 减少高热量、低营养食品的摄入； c) 提高体力水平 活动。这些目标将通过将 360 名儿童随机分配到以下两种治疗条件之一来实现：a) 体内！ MEI 基于电话和互联网的家长治疗计划； b) 无治疗对照。我们 将检查所选饮食、久坐和体力活动行为的积极变化是否会导致 体重增加减少以及与 2 型糖尿病相关的危险因素减少。拟议项目将影响：a) 体重指数 (BMI)，b) C 反应蛋白 (CRP)，c) 胰岛素抵抗，d) HbA1c，以及 e) 行为 以及这些身体措施的心理社会先兆。家庭将被随机分配参加 STPDPT 条件或对照组；治疗组的患者将接到 6-9 个 MEI 电话以及后续跟进 12 个月内通过互联网、时事通讯和漫画书进行的联系。研究目的： 1) 进行 与家长、教师和学生进行访谈，以确定 MEI 电话和互联网的总体可行性 父母糖尿病预防策略（2007 年秋季）； 2）对200名家长进行横断面调查 南德克萨斯州下里奥格兰德河谷扩展并确认目标 1 的发现（2008 年春季）； 3) 至 使用试点数据为家长量身定制基于 MEI 的家长计划（2008 年夏季）； 4）评估影响 基于 MEI 的家长计划，采用随机方法对 9-14 岁儿童的生理和行为结果进行评估 临床试验方法，从 Cameron 成员中招募了 360 个家庭（父母/孩子） 县西班牙裔群体（2008 年秋季 - 2011 年）。

The proposed Center of Excellence on Diabetes in Americans of Mexican Descent aims to conduct research on the physiologic progression to diabetes and its complications among Mexican Americans, and to develop diabetes prevention strategies and test innovative approaches to effective interventions in a minority population severely affected by type 2 diabetes. This Center proposes an administrative core, a research core including three research projects and two pilot studies, a training core and a community engagement core. As part of the research core, the South Texas Parent Diabetes Prevention Trial (STPDPT) aims to test the effectiveness of a brief motivational enhanced interview (MEI) treatment aimed at parents to modify the home environment so that their children will: a) reduce "screen time" or hours engaged in sedentary behaviors; b) reduce consumption of high calorie, low nutrient foods; and c) increase levels of physical activity. These aims will be accomplished by randomizing 360 children to one of two treatment conditions: a) the En Vivo! MEI telephone and Internet based parent treatment program; and b) no-treatment control. We will examine if positive changes in selected dietary, sedentary and physical activity behaviors result in decreased weight gain and risk factors associated with type 2 diabetes. The proposed project will impact: a) body mass index (BMI), b) C-reactive protein (CRP), c) insulin resistance, d) HbA1c, as well e) behavioral and psychosocial precursors to these physical measures. Families will be randomized to the STPDPT condition or a comparison group; those in the treatment group will receive 6-9 MEI phone calls plus follow-up contact via the Internet and newsletters and comic books over a 12 month period. Study Aims: 1) To conduct interviews with parents, teachers, and students to determine overall feasibility of MEI telephone and Internet parent diabetes prevention strategies (Fall, 2007); 2) To conduct a cross sectional survey of 200 parents in the South Texas Lower Rio Grande Valley to extend and confirm findings from Aim 1 (Spring, 2008); 3) To use pilot data to tailor the MEI based parent program for parents (Summer 2008); 4) To assess the impact MEI based parent program on physiologic and behavioral outcomes on children aged 9-14 using randomized clinical trial methodology with 360 families (parent/child dyad) recruited from members of the Cameron County Hispanic Cohort (Fall 2008 - 2011).