CYCLODEXTRIN-ENHANCED FLUORESCENCE OF POLYAROMATIC HYDROCARBONS

这个子项目是众多研究子项目之一

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The enhancement of fluorescence of aqueous solutions of several polyaromatic hydrocarbons (PAH) by complexation with cyclodextrin is investigated. Specifically, we are interested in PAH of different molecular size and solubility complexed with alpha and beta cyclodextrin. Quenching of fluorescence will be assessed by generation of Stern-Volmer plots for both the complexes and the free PAH, and fluorescence lifetimes for both the complexes and free PAH will be measured in order to show to what extent the shielding of the fluorophore from the solvent, thought to be the primary mechanism of fluorescence enhancement by cyclodextrin complexation, accounts for changes in the fluorescence quantum efficiencies or the fluorescence lifetimes.