CYCLODEXTRIN-ENHANCED FLUORESCENCE OF POLYAROMATIC HYDROCARBONS

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。研究了环糊精对多环芳烃水溶液荧光的增强作用。具体而言，我们感兴趣的是不同分子大小和溶解度的PAH与α和β环糊精复合。通过生成复合物和游离PAH的Stern-Volmer图来评估荧光的淬灭，并测量复合物和游离PAH的荧光寿命，以显示荧光团对溶剂的屏蔽程度，这被认为是环糊精复合的荧光增强的主要机制，解释了荧光量子效率或荧光寿命的变化。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The enhancement of fluorescence of aqueous solutions of several polyaromatic hydrocarbons (PAH) by complexation with cyclodextrin is investigated. Specifically, we are interested in PAH of different molecular size and solubility complexed with alpha and beta cyclodextrin. Quenching of fluorescence will be assessed by generation of Stern-Volmer plots for both the complexes and the free PAH, and fluorescence lifetimes for both the complexes and free PAH will be measured in order to show to what extent the shielding of the fluorophore from the solvent, thought to be the primary mechanism of fluorescence enhancement by cyclodextrin complexation, accounts for changes in the fluorescence quantum efficiencies or the fluorescence lifetimes.