NON-CONTACT CHARACTERIZATION OF RED BLOOD CELL MECHANICAL PROPERTIES

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 希尔伯特位相显微镜(HPM)是我们实验室发展起来的一种新的成像技术，它能够以完全非侵入性的方式提供关于纳米和毫秒级红细胞波动的定量信息。我们开发了一种 一种数学算法，允许从空间分辨的均方波动中提取物理参数，如薄膜弯曲模数。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Hilbert phase microscopy (HPM) is a novel imaging technique developed in our lab that is capable of providing quantitative information about the red blood cells fluctuations at the nanometer and millisecond level, in a completely non-invasive manner. We developed a mathematical algorithm which allows extracting physical parameters, such as the membrane bending modulus, from the spatially resolved mean squared fluctuations.