INTRACELLULAR HEAVY METAL LOCALIZATION IN ARABIDOPSIS

拟南芥细胞内重金属定位

• 批准号: 7601073
• 负责人: JULIAN I SCHROEDER
• 金额: $ 1.09万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-05-01 至 2008-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7601073
• 关键词: Affect; Arabidopsis; Cadmium; Computer Retrieval of Information on Scientific Projects Database; Copper; Funding; Glutathione; Grant; Heavy Metals; Institution; Localized; Mouse-ear Cress; Peptides; Plant Roots; Plants; Research; Research Personnel; Resources; Role; Source; United States National Institutes of Health; mutant; phytochelatin

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. During the course of investigating the role of phytochelatins, glutathione-derived peptides, in cadmium inactivation and translocation in plants it was found that the phytochelatin deficient mutant cad1-3 (Arabidopsis thaliana, Col ecotype) overaccumulates copper in roots. Such accumulation is dependent upon cadmium exposure and does not affect the copper content in shoots, either before or after cadmium exposure. It is intended to use the NCMIR to localize the intracellular compartment in which copper is being accumulated.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 在研究谷胱甘肽衍生肽植物螯合素在植物镉失活和转运中的作用过程中，发现植物螯合素缺陷突变体cad 1 -3（Arabidopsis thaliana，Col生态型）在根中过量积累铜。这种积累依赖于镉暴露，并不影响芽中的铜含量，无论是之前或之后镉暴露。其旨在使用NCMIR定位铜蓄积的细胞内区室。