ANALYSIS OF EXOSOMES FROM CISPLATIN RESISTANT AND SENSITIVE OVARIAN CANCER

顺铂耐药和敏感卵巢癌外泌体分析

• 批准号: 7601067
• 负责人: STEPHEN B HOWELL
• 金额: $ 0.65万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-05-01 至 2008-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7601067
• 关键词: Cells; Cisplatin; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Institution; Malignant neoplasm of ovary; Research; Research Personnel; Resistance; Resources; Source; United States National Institutes of Health

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We have discovered that cisplatin (DDP) resitant cells release a distinct type of exosomes which are enriched in efflux transporters. We would like to begin characterizing these exosomes.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 我们已经发现顺铂（DDP）耐药细胞释放富含外排转运蛋白的独特类型的外泌体。我们想开始鉴定这些外来体。