CRYSTAL SCREENING

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 BioCARS正在提供一系列晶体筛选诊所，在那里，当地用户群体能够在短时间内评估新晶体。晶体生长和优化的一个重要部分是评估新的晶体形态。这一过程通常是在家庭机构的旋转阳极上费力地完成的。我们建议在APS进行这种筛选，因为同步辐射的光束强度和质量都增加了。除了大大加快了这一过程，在APS获得的衍射图应该能更好地反映晶体质量。 事实证明，我们以前的诊所对当地用户非常受欢迎和有用。我们只向经过当前培训的注册APS用户提供这些诊所，因此基本上所有收集的数据都将与不同的一般用户建议相关联。绝对不允许有危险的样品或材料，因为收集了不同的用户群体，并在短时间内通知增加新的样品和人员。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. BioCARS is offering a series of crystal screening clinics, where local user groups are able to evaluate new crystals at short notice. An important part of crystal growth and optimization is evaluating new crystal forms. This process is usually painstakingly done on a rotating anode at the home institution. We propose to do this screening at the APS because of the increased beam intensity and quality of synchrotron radiation. Besides greatly speeding up the process, diffraction images obtained at the APS should give a better indication of crystal quality. Our previous clinics have proven very popular and useful to local users. We are only offering these clinics to registered APS users with current training, so essentially all of data being collected will be associated with different general user proposals. Absolutely no hazardous samples or materials will be allowed given the collection of different user groups and short notice for addition of new samples and personnel.