MOLECULAR DISSECTION OF CONTRACTILE RING ASSEMBLY AND FUNCTION IN C ELEGANS

线虫收缩环组装和功能的分子解剖

• 批准号: 7602209
• 负责人: Amy Shaub Maddox
• 金额: $ 0.62万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-01 至 2008-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7602209
• 关键词: Anaphase; Cell division; Chromosome Segregation; Computer Retrieval of Information on Scientific Projects Database; Cytokinesis; DNA; Dissection; F-Actin; Funding; Grant; Institution; Mitosis; Molecular; Myosin Type II; Placement; Regulation; Research; Research Personnel; Resources; Signal Transduction; Source; Time; United States National Institutes of Health; daughter cell

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Following chromosome segregation in mitosis, the two masses of DNA must be physically segregated into the daughter cells. This physical cell division is Cytokinesis. Signals from the anaphase spindle elicit assembly of a ring rich in filamentous actin and myosin II around the equatorial cortex. We are studying the regulation of the timing and placement of the assembly of this contractile ring, as well as its composition.

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