AUTOMATED SPECIMEN HANDLING

自动样本处理

• 批准号: 7602714
• 负责人: CLINTON S POTTER
• 金额: $ 5.37万
• 依托单位: SCRIPPS RESEARCH INSTITUTE, THE
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-08-13 至 2008-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7602714
• 关键词: Computer Retrieval of Information on Scientific Projects Database; Crystallography; Development; Electron Microscopy; Funding; Grant; Institution; Methods; Microscope; Molecular; Proteins; Research; Research Personnel; Resources; Robotics; Sampling; Source; Specimen; Specimen Handling; Staging; System; United States National Institutes of Health; prototype

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This project focuses on the development of a robotic system for loading grids into the specimen stage and subsequently loading the stage into the microscope. Automated methods have been a critical component in the rapid development of high throughput methods for protein crystallography. Our objective is to prototype similar automated sample handling methods for molecular electron microscopy.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 该项目的重点是开发一个机器人系统，用于将网格加载到样本台中，然后将平台加载到显微镜中。 自动化方法一直是蛋白质晶体学高通量方法快速发展的关键组成部分。我们的目标是为分子电子显微镜建立类似的自动化样品处理方法的原型。