Physician & Scientist Training in Developmental Genetics

描述（由申请人提供）：塔夫茨新英格兰医学中心（T-NEMC）和塔夫茨大学医学院（TUSM）的发育遗传学培训计划将为医生和博士前学生提供发育遗传学和遗传性疾病遗传学方面的强大培训，这些遗传学可能会影响胎儿，新生儿和孕产妇健康。 拟议的25名教师来自T-NEMC和TUSM，包括持有医学博士学位的基础和翻译研究人员，博士，M.D.博士度 三名博士后学员将从ACGME认证的奖学金计划在母胎医学，新生儿围产期医学，医学遗传学在T-NEMC的基础上招募，三名博士前学员将从博士招募。在遗传学和细胞和分子生理学的课程在萨克勒研究生院生物医学科学在TUSM每年。 学员将分享一个共同的培训经验，严格接触到板凳和翻译研究。 该计划将促进儿科医生，医学遗传学家和治疗患者的产科医生以及专注于疾病遗传机制的基础科学家之间的互动，从而帮助每个小组了解对方工作的影响。 研究培训将辅之以关于遗传学基础、发育遗传学、伦理学的共同课程，以及由基础科学家和医生共同讲授的关于遗传和发育疾病的病理生物学的课程。 研讨会，演讲研讨会，医院为基础的遗传学轮，和职业咨询轮的程序。 通过整合基础和临床教师，拟议的学员将获得基本遗传机制和当代临床问题的更深层次和更丰富的知识。 目标是培养能够在多学科、翻译环境中富有成效的基础科学教师和临床科学家，他们将成为独立的、受资助的研究人员，解决与有发育障碍或遗传性疾病风险的母亲和儿童的健康相关的问题。

DESCRIPTION (provided by applicant): The Developmental Genetics Training Program at Tufts New England Medical Center (T-NEMC) and Tufts University School of Medicine (TUSM) will provide physicians and predoctoral students with strong training in developmental genetics and the genetics of inherited diseases that can impact fetal, neonatal, and maternal health. The proposed faculty of 25 is drawn from T-NEMC and TUSM, and includes basic and translational researchers who hold M.D., Ph.D., and M.D./Ph.D. degrees. Three postdoctoral trainees will be recruited from the ACGME-accredited fellowship programs in Maternal-Fetal Medicine, Neonatal-Perinatal Medicine, and Medical Genetics based at T-NEMC, and three predoctoral trainees will be recruited from the Ph.D. programs in Genetics and Cellular and Molecular Physiology at the Sackler School of Graduate Biomedical Sciences at TUSM each year. Trainees will share a common training experience with rigorous exposure to bench and translational research. The program will promote interaction among pediatricians, medical geneticists, and obstetricians who treat patients and basic scientists who focus on genetic mechanisms of disease, thereby helping each group understand the impact of the other's work. Research training will be complemented by common courses on fundamentals of genetics, developmental genetics, ethics, and a course on the pathobiology of genetic and developmental diseases that is co-taught by basic scientists and physicians. Seminars, presentation workshops, hospital-based genetics rounds, and career counseling round out the program. By integrating basic and clinical faculty, the proposed trainees will acquire a deeper and richer knowledge of basic genetic mechanisms and contemporary clinical problems. The goal is to produce basic science faculty who can be productive in multidisciplinary, translational environments and clinician scientists who will be become independent, funded investigators addressing problems relevant to the health of mothers and children at risk for developmental disability or inherited disorders.