Stability of Coping and Memory for Social Stress

社交压力应对和记忆的稳定性

• 批准号: 7585664
• 负责人: Ed Tronick
• 金额: $ 53.44万
• 依托单位: BOSTON CHILDREN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-06-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7585664
• 关键词: Address; Adopted; Adult; Affect; Affective; Age; Age-Months; Analysis of Variance; Animals; Applications Grants; Area; Attention; Behavior; Behavior assessment; Behavioral; Brain; Caregivers; Characteristics; Child; Chronic; Code; Control Groups; Coping Behavior; Coupled; Critiques; Data; Development; Developmental Process; Drops; Emotional; Equilibrium; Evaluation; Event; Exhibits; Exposure to; Face; Female; Frequencies; Gender; Goals; Grant; Hiccup; High birth weight infant; Human; Hydrocortisone; Individual Differences; Infant; Infant Behavior; Institution; Interdisciplinary Study; Intervention; Length; Life; Literature; Living Wills; Measurement; Measures; Memory; Methods; Mothers; Nature; Neurosciences; Parents; Pediatrics; Phase; Physiological; Physiology; Play; Policies; Population; Psychiatry; Psychologist; Psychopathology; Psychophysiology; Published Comment; Qualifying; Questionnaires; Randomized; Reaction; Reaction Time; Regression Analysis; Regulation; Relative (related person); Reporting; Research; Research Design; Research Personnel; Salivary; Sampling; Shapes; Social Interaction; Statistical Models; Stimulus; Stress; System; Techniques; Temperament; Thumb Sucking; Time; Toddler; Translational Research; Trauma; Variant; Videotape; Visit; Work; age effect; age related; base; behavior measurement; coping; design; emotional reaction; exhibitions; experience; gaze; high risk; improved; male; memory process; pre-clinical; respiratory; response; social; social stress; stressor; time interval

DESCRIPTION (provided by applicant): The primary aims of this grant are to: (1) evaluate the stability of individual differences in infants' behavior (positive and negative engagement, self-regulatory behaviors), vagal tone and cortisol response assessed during a social stress, maternal Face-to-Face Still-Face Paradigm over a 3- or a 6-month time interval; (2) evaluate infants' memory for the still-face over the 3- or 6-month time interval; and (3) evaluate the relation between infant reactivity and memory. Ten independent groups of mother-infant dyads (N = 340, n = 34 per group) balanced for infant gender will comprise the sample. Six groups will be randomly assigned to an experimental condition. For infants in the experimental condition, the 1st exposure to the FFSF will take place when the infants are 6, 9, or 12 months of age, and their respective 2nd exposure will be either 3 or 6 months later, at 9, 12, 15 or 18 months of age. Infants in the control condition will be videotaped once in the FFSF, at the age corresponding to the 2nd exposure for infants in the experimental conditions (at 9, 12, 15, or 18 months of age). For all groups measures of infant gaze during the SF will be coded as a measure of memory. Infants' vagal tone (VT), cortisol response, and negative engagement states and self-regulatory behaviors during the FFSF paradigm will be scored microanalytically from videotapes will be collected at each visit as measures of reactivity. Variations in infants' cardio-respiratory activity (vagal tone) will be assessed using the method developed by Porges, and cortisol response will be measured using salivary cortisol with methods developed by Gunnar. A measure of infant perceived temperament will be derived at each visit from temperament questionnaires completed by the mother: the Infant Behavior Questionnaire (IBQ) for infants at 6, 9, or 12 months and the Toddler Assessment of Behavior Questionnaire (TABQ) for infants at 15 or 18 months of age. This study will provide valuable longitudinal on a standard and widely used stress paradigm and make a significant contribution to our understanding the stability of individual differences in infants' behavior, affect, physiological regulation, and memory during social stress.

描述（申请人提供）：本基金的主要目的是：（1）评估婴儿行为个体差异的稳定性（积极和消极的参与，自我调节行为），迷走神经张力和皮质醇反应评估期间的社会压力，母亲面对面静止面孔范式超过3个月或6个月的时间间隔;（2）评估婴儿在3个月或6个月的时间间隔内对静止面孔的记忆;（3）评估婴儿反应性与记忆之间的关系。10个独立的母婴配对组（N = 340，每组n = 34），婴儿性别平衡，将包括样本。将六个组随机分配到一个实验条件下。对于实验条件下的婴儿，第一次暴露于FFSF将发生在婴儿6、9或12个月大时，其各自的第二次暴露将在3或6个月后，9、12、15或18个月大时。对照条件下的婴儿将在FFSF中进行一次录像，年龄对应于实验条件下婴儿的第2次暴露（9、12、15或18月龄）。对于所有组，SF期间婴儿凝视的测量将编码为记忆的测量。在FFSF范例期间，婴儿的迷走神经张力（VT）、皮质醇反应和负性参与状态以及自我调节行为将在每次访视时从录像带中进行微分析评分，作为反应性指标。将使用Porges开发的方法评估婴儿心肺活动（迷走神经张力）的变化，并使用Gunnar开发的方法使用唾液皮质醇测量皮质醇反应。每次访视时，将从母亲完成的气质问卷中获得婴儿感知气质的测量值：6、9或12月龄婴儿的婴儿行为问卷（IBQ）和15或18月龄婴儿的幼儿行为评估问卷（TABQ）。本研究将提供一个标准的和广泛使用的压力范式的有价值的纵向研究，并为我们理解社会压力下婴儿行为、情感、生理调节和记忆的个体差异的稳定性做出重要贡献。