Duke Training Grant in Nephrology

描述(由申请人提供)： 杜克大学肾病学培训助学金的目的是为博士后提供与正常肾脏生理、肾脏疾病的发病机制和高血压相关的强化研究培训。该计划的长期目标是培养具有肾脏病研究专长的学术内科医生和基础科学家。该计划为基础和临床研究提供不同的培训机会，使受训者能够发展必要的技能和灵活性，以应对未来几年的肾脏病学研究需求。我们的教师在一系列学科中拥有广泛的兴趣和专业知识，提供生理学、分子和细胞生物学、生物化学和转基因小鼠技术方面的综合培训。对于对临床研究感兴趣的学员，正在进行的生物识别、决策分析和人类遗传学课程为与高血压和肾脏疾病相关的临床问题提供了学术评估的基础。我们认为，获得研究技能的最佳方式是与质量指导密切合作的两到三年密集的实验室经验，该计划的结构是在导师的监督下最大限度地延长实验室时间。对于拥有医学博士学位的学员，该计划包括一年的临床培训和至少两年的研究培训，这些培训将由本申请中申请的资金支持。正规的课程作业、研讨会和杂志俱乐部是对这一实验经验的补充。完成这一计划将使受训人员能够从事从事高质量临床和基础肾脏病学研究的院士职业。

DESCRIPTION (provided by applicant): The purpose of the Duke Training Grant in Nephrology is to provide intensive research training for postdoctoral fellows in areas that relate to normal kidney physiology, the pathogenesis of diseases of the kidney, and hypertension. The long-term goal of the program is to produce academically oriented physicians and basic scientists with investigative expertise in nephrology. The program provides diverse opportunities for training in basic and clinical research allowing trainees to develop the skills and flexibility necessary to respond to research demands in nephrology over the coming years. Our faculty have a wide range of interests and expertise in an array of disciplines providing integrated training in physiology, molecular and cell biology, biochemistry, and transgenic mouse technologies. For trainees interested in clinical research, ongoing programs in biometrics, decision analysis, and human genetics provide a basis for academic evaluation of clinical issues related to hypertension and diseases of the kidney. We feel that the acquisition of research skills is best accomplished by two to three years of intensive laboratory experience working closely with a quality preceptor and the program is structured to maximize time in the laboratory under the supervision of a mentor. For trainees with M.D. degrees, the program consists of one year of clinical training followed by at least two years of research training that will be supported by funds requested in this application. Formal course work, seminars, and journal clubs supplement this laboratory experience. Completion of this program should allow trainees to pursue careers as academicians conducting high-quality research in clinical and basic aspects of nephrology