ADMINISTRATIVE

行政核心将向本组织的每个项目和核心提供管理服务 程序。该核心将为PI，即共同PI项目提供财务、行政和文书服务 领导，以及所有与赠款相关活动的核心领导。这些活动包括准备这个 竞争性续签、非竞争性续签，包括进度报告、预算编制、 与NIH就续签和所有财务互动进行沟通，并保证实验室 由本计划支持，完全符合所有机构、州和联邦法规。核心A 还将协调和安排与方案职能有关的所有会议，包括每月一次 所有项目和核心领导人及其各自实验室成员的会议，以及两次 内部和外部咨询委员会的年度会议。核心A还将与场外协调工作 Brigham和妇女医院，以色列Beth-Deaconess三家邻近机构的调查人员 访问了波士顿儿童医院，并与DFCI的调查人员进行了互动。Dr。 吉利兰是这个核心的PI和主任，并将担任总的科学主任和首席 管理员。格里芬博士是联合PI，他将协助这些行动，特别是在事务方面 与DFCI的现场调查人员和临床项目合作。他将协助吉利兰博士监测 协议性能，并将协助协议开发。阿尔贝托·贾马里洛是一位技艺高超的 具有大型项目财务和行政事务管理经验的管理员 资助金。他将担任行政协调员，并协调计划的行政和财务 吉利兰医生和格里芬医生的监督。Alberto Jamarillo将由Grants的Betsy Kelley协助 管理专家/岗位奖，行政助理Mariha Duarte，与Dr。 为了管理参与机构之间的预算，吉利兰和格里芬博士准备了包括非竞争性在内的报告 续签，与方案中每个参与机构的财务官员联系，以及 作为这些组织和NIH之间的接口。此外，行政核心将确保 遵守有关人体试验的适当法规(包括性别 和少数人参与)和脊椎动物。

The Administrative Core will provide management services to each of the Projects and Cores in this Program. The Core will provide financial, adminstrative, and clerical services for the PI, the Co-Pi, Project Leaders, and Core Leaders for all grant-related activities. These activites include the preparation of this competing renewal, non-competing renewals including progress reports, preparation of budgets, communication with the NIH regarding renewals and all financial interactions, and assurance that the labs supported by this Program are in full compliance with all institutional, state and federal regulations. Core A will also coordinate and scheduling all meetings related to the function of the Program, including monthly meetings of all Project and Core Leaders, and members of their respective laboratories, as well as twice yearly meetings of the Internal and External Advisory Boards. Core A will also coordinate efforts with off-site investiators at the three neighboring institutions, Brigham and Women's Hospital, Beth Israel-Deaconess Hospital, and Children's Hospital of Boston, as well as interaction with the investigators at the DFCI. Dr. Gilliland is the PI and Director of this Core, and will serve as the overall scientific director and chief administrator. Dr. Griffin is the Co-Pi and will assist in these operations, particaulrly with regard to matters with the on-site investigators and clinical programs at the DFCI. He will assist Dr. Gilliland in monitoring protocol performance and will assist in protocol development. Alberto Jamarillo is a highly skilled administrator with experience in management of fiscal and administrative matters for large program project grants. He will serve as Administrative Facilitator, and coordinate Program administration and fiscal oversight with Dr. Gilliland and Dr. Griffin. Alberto Jamarillo will be assisted by Betsy Kelley, a Grants Management Specialist/Post Award, and Mariha Duarte, an administrative assistant, in coordination with Dr. Gilliland and Dr. Griffin, to manage budgets between participating institutions, prepare reports including noncompeting renewals, interface with the financial officers of each participating institution in the Program, and serve as an interface between these groups and the NIH. In addition, the Administrative Core will assure compliance with appropriate regulations regarding experimentation with human subjects, (including gender and minority participation) and vertebrate animals.