Boston University Clinical and Translational Science Award (CTSA) Program UL1

波士顿大学提议建立一个临床和转化科学研究所，即BU-BRIDGE研究所， 这将整合，连接和扩展我们目前的研究和大学计划，从而提供一个 下一代临床和翻译研究人员的学术和知识之家。研究所 将围绕五个部门组织：1）转化科学孵化器; 2）信息学; 3）临床研究 增强; 4）社区参与;和5）研究教育和培训。这五个部门 是专门设计来支持双向发展和思想的翻译，开始在 从而产生新相关工具来改善健康、健康 护理和分娩。BU-BRIDGE将实现五个具体目标：1）协调现有的和确定新的 现有BU科学家之间的合作，有可能发展成为多学科的翻译 计划，并促进BU“一站式购物”计划，以创造知识产权， （2）支持现有的和正在开发的技术的进一步发展; 通过试点赠款网络创建新的翻译方案和核心。3)提供新的和现有的 临床和转化研究计划，具有扩展和丰富的基于BU-BRIDGE的菜单 机构支持，包括改进的、方便用户的医疗信息系统（数据库）， 从我们的GCRC到社区人群的研究，提供了一个综合的方法，伦理，监管 问题，研究设计，分析和实施卫生干预措施4）提供渠道， 在临床医生、临床和基础科学家之间进行定向的思想交流，以更充分地参与社区 在研究过程中，包括确定调查的优先次序，设计研究，确保道德 根据研究结果进行研究并实施最佳实践; 5）作为培训中心 下一代的研究人员与适当的工具，将基础科学转化为临床研究。的 新学院是超越传统院系的跨校实体。它将 多个重点大学项目，包括国家新发传染病实验室， 心脏研究，波士顿大学技术开发商业化组合办公室， 生物医学工程和生物信息学，萨金特联合卫生专业人员学院，波士顿卫生 Net，波士顿医疗中心和VA医院，支持大学范围内的家庭承诺， 翻译研究CTSA奖将提供资源，通过利用 现有的优势，以创造一个环境，将新的想法，教师，学员和大学课程， 加速医学科学的创新。BU-BRIDGE的使命与公共卫生有关，因为它将 加强地方和国家社区成员可用的医疗保健实践的发展。

Boston University proposes to create a Clinical and Translational Science Institute, the BU-BRIDGE Institute, that will integrate, connect and expand our current researchand university programs and, thereby, provide an academic and intellectual home for the next generation of clinical and translational investigators. The Institute will be organized around five Divisions: 1} Translational Science Incubator; 2) Informatics; 3) Clinical Research Enhancements; 4) Community Engagements; and 5) Research Education and Training. These five divisions are specifically designed to support the bi-directional development and translation of ideas that begin in the laboratory or bedside move seamlessly back and forth to result in new relevant tools to improve health, health care and delivery. The BU-BRIDGE will accomplish five specific aims: 1) Coordinate existing and identify new collaborations among existing BU scientists with the potential to develop into multidisciplinary translational programs, and facilitate the BU "one stop shopping" program for creating intellectual property and commercialization of translational scientific ideas; 2) Support the further development of existing and the creation of new translational programs and cores through a network of pilot grants. 3) Provide new and existing Clinical and Translational research programs with an expanded and enriched menu of BU-BRIDGE-based institutional support, including an improved, user friendly medical informatics syslem (warehouse), expansion of research from our GCRC into community populations, provide an integrated approach to ethics, regulatory issues, study design, analysis and implementation of health interventions 4) Provide the conduit for bi- directional flow of ideas between clinicians and clinical and basic scientists to more fully engage the community in the research process including setting priorities for investigation, designing studies, ensuring ethical research conduct and implementing best practices based on study results; 5) Serve as the Center for training the next generation of investigators with the proper tools to translate basic science into clinical research. The new institute is cross University entity that supercedes traditional departments and schools. It encorporates multiple key university programs including the National Emerging Infectious Diseases Laboratory, Framingham Heart Study, Boston University Office of Technology Development Commercialization portfolio, Departments of Biomedical Engineering and Bioinformatics,Sargent College of Allied Heath Professionals,the Boston Health Net, Boston Medical Center and VA Hospitals that support the university wide commitment for a home for translational research. The CTSA award will provide the resources to transform the institute by leveraging existing strengths to create an environment that will link new ideas,faculty, trainees and university programs to speed innovations in medical science. The mission of the BU-BRIDGE is relevant to the public health as it will enhance the development of healthcare practices availableto members of the local and national communities.