Predictors of HIV Risk Behavior Among Men in Argentina

阿根廷男性艾滋病毒风险行为的预测因素

• 批准号: 7684086
• 负责人: Alex CARBALLO-DIEGUEZ
• 金额: $ 15.63万
• 依托单位: NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-16 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7684086
• 关键词: AIDS diagnosis; AIDS prevention; AIDS/HIV diagnosis; AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Address; Adult; Affect; Age-Years; American; Americas; Area; Argentina; Brazil; Caring; Cessation of life; Cities; Civil Rights; Cognitive; Collaborations; Communities; Country; Data; Data Analyses; Data Collection; Dedications; Development; Diagnosis; Emotional; Environmental Risk Factor; Epidemic; Epidemiologic Studies; Focus Groups; Fostering; Foundations; Future; Gatekeeping; Gays; HIV; HIV Infections; HIV Seropositivity; Human immunodeficiency virus test; Incidence; Individual; Infection; International; Interview; Knowledge; Latin America; Lawyers; Life; Logistic Regressions; Methods; Mexico; Nature; New York; New York City; Pattern; Phase; Population; Positioning Attribute; Preparation; Prevalence; Prevention; Prevention program; Principal Investigator; Psychiatrist; Psychologist; Qualifying; Recruitment Activity; Research; Research Personnel; Resources; Respondent; Risk; Risk Behaviors; Sampling; Serologic tests; Services; Sexually Transmitted Diseases; Site; Solid; South America; South American; Staging; System; Technology; Testing; Universities; Unsafe Sex; Work; base; boletin; contextual factors; design; experience; fighting; high risk; high risk men; insight; intervention program; male; man; meetings; men; men who have sex with men; metropolitan; news; population based; programs; psychologic; psychosocial; sex risk; sound; statistics; symposium; theories; virology

DESCRIPTION (provided by applicant): Although the AIDS epidemic has not devastated Latin America to the degree seen in other parts of the world, there is concern that unless consistent prevention efforts are made now it can wreak havoc on the continent in the coming decade. In Argentina, it is estimated that there are 130,000 HIV-infected adults resulting in a prevalence rate of 0.7%, which matches Brazil's for highest in South America. Among high-risk men, HIV prevalence can reach as high as 13.8%. Yet, there is a dearth of knowledge concerning psychosocial and contextual factors associated with unsafe sex on which to base HIV-prevention programs. This gap in knowledge will be addressed by our study. Targeting high-risk men living in Buenos Aires, the Primary Aims of our study are to (1) assess cognitive, emotional, socio-cultural, and contextual predictors of HIV-related risk behavior; (2) assess patterns of HIV testing in the high-risk male population and factors that facilitate or hinder testing; and (3) assess prevalence and incidence of HIV and STI infections. Overall, the study seeks to foster a mutually enriching collaborative relationship between the US- and Argentina-based research partners on which to build a future intervention program to decrease risk behavior among men in Argentina. This will be a 4.5- year study consisting of two phases: a formative phase and an assessment phase. The formative phase, which will be qualitative in nature, will consist of: (a) individual in-depth interviews with System Representatives and Gatekeepers; (b) focus groups and individual interviews with high risk men; and (c) site observations of places where men meet. During the assessment phase, 500 systematically recruited men from the Buenos Aires metropolitan area will undergo (a) a theoretically-based assessment of risk behavior and its psychosocial and contextual predictors as well as barriers and facilitators of HIV testing, and (b) HIV and STI testing. During this assessment phase, we will use both Respondent Driven Sampling to recruit an unbiased sample and CASI technology to minimize respondent bias. Grounded theory will guide the qualitative data analysis, and quantitative data analysis will include GLM, GEE, and linear and logistic regression methods. By the end of the study, we will have solid data that will serve as the basis for the development of HIV prevention programs specifically designed for high-risk men in Buenos Aires. This study will contribute to identifying psychological, cultural, and environmental factors that encourage HIV-risk behavior among men in Argentina. This is a fundamental step prior to designing programs that mitigate those factors and result in decreased risk.

描述(申请人提供)：虽然艾滋病疫情对拉丁美洲的破坏程度还没有达到世界其他地区的程度，但人们担心，除非现在做出持续的预防努力，否则它可能在未来十年对该大陆造成严重破坏。在阿根廷，估计有13万成年人感染艾滋病毒，导致感染率为0.7%，与巴西在南美洲的最高水平不相上下。在高危男性中，艾滋病毒流行率可高达13.8%。然而，缺乏关于与不安全的性行为相关的心理社会和背景因素的知识，以此作为艾滋病毒预防计划的基础。这一知识差距将通过我们的研究来解决。针对居住在布宜诺斯艾利斯的高危男性，我们研究的主要目的是(1)评估艾滋病毒相关危险行为的认知、情感、社会文化和背景预测因素；(2)评估高危男性人群中艾滋病毒检测的模式以及促进或阻碍检测的因素；以及(3)评估艾滋病毒和性传播感染的流行率和发病率。总体而言，这项研究试图在美国和阿根廷的研究伙伴之间建立一种互惠互利的合作关系，在此基础上建立未来的干预计划，以减少阿根廷男性的风险行为。这将是一项为期4.5年的研究，包括两个阶段：形成阶段和评估阶段。形成阶段将是定性的，将包括：(A)对系统代表和看门人进行个别深入访谈；(B)重点小组和对高风险男子的个别访谈；(C)对男子相遇地点的实地观察。在评估阶段，从布宜诺斯艾利斯大都市区系统招募的500名男子将接受：(A)对危险行为及其心理社会和背景预测因素以及艾滋病毒检测的障碍和促进者的理论评估；(B)艾滋病毒和性传播感染检测。在这个评估阶段，我们将使用受访者驱动抽样来招募无偏见的样本，并使用CASI技术来最大限度地减少受访者的偏见。扎根理论将指导定性数据分析，定量数据分析将包括GLM、GEE、线性和Logistic回归方法。到研究结束时，我们将拥有坚实的数据，这些数据将成为开发专门为布宜诺斯艾利斯高危男性设计的艾滋病毒预防计划的基础。这项研究将有助于确定鼓励阿根廷男性艾滋病毒风险行为的心理、文化和环境因素。这是在设计缓解这些因素并降低风险的计划之前的基本步骤。