BIOINFORMATICS

生物信息学核心（BIC）成立于2003年初，旨在建立和提供生物信息学服务， 基础设施演进为MSK研究者提供的生物信息学服务和基础设施包括 科学咨询、培训、高性能计算和发展机构 资源，由6名全职工作人员提供，由科学主任和助理主任领导， 以机构领导为导向。由于这种基础设施的发展取决于使用， 以及与现有外部生物信息学数据库、软件和标准的互操作性，BIC还 率先MSK参与NCI的caBIG倡议。在运营的头几年里，BIC已经 广泛融入MSK研究者领导的基础、临床和转化研究。这 集成体现在服务使用的广度和深度上， 生物信息学专业人员提供。在未来五年内，我们预计生物信息学的需求， 生物信息学研究所将逐步发展壮大，但也注意到对生物信息学服务和资源的需求日益增加 随着生物医学数据的数量和复杂性不断增长-特别是根据NIH的癌症 基因组图谱倡议（TCGA）。

The Bioinformatics Core (BIC) was created in early 2003 to build and provide bioinformatics services and infrastructure. The bioinformatics services and infrastructure provided to MSK investigators include scientific consultations, training, high performance computing and the development of institutional resources, and is provided by 6 fulltime staff members, lead by scientific director and assistant director, and guided by institutional leadership. Because the development of this infrastructure depends on the use of, and interoperability with existing external bioinformatics databases, software and standards, BIC has also spearheaded MSK involvement in the NCI caBIG initiative. Over the first several years of operation, BIC has become widely integrated into MSK investigator led basic, clinical and translational research. This integration is manifest by the breadth and depth of the usage of the services that its diverse group of bioinformatics professionals provides. Over the next five years, we expect the bioinformatics needs of the institution to grow gradually, but are mindful of the increased need for bioinformatics services and resources as the amount and complexity of biomedical data continues to grow - especially in light of NIH's The Cancer Genome Atlas initiative (TCGA).