Core 2 - Rapid Multipathogen Detection For POCT and Natioal Disaster Readiness

核心2。确定合作探索项目的计划 探索性POCT技术项目的时间轴。核心2将产生新的 与核心3的关键紧急情况/灾难主题相一致的病原体检测技术 在乎核心2包括总共六个探索性项目： 在期限方面，B）一个18个月项目，和c）一个一年项目。第一轮核心 两个奖项将在年初公布。第一个项目将于2008年4月1日开始。 四个核心2项目中的第一个项目于第一年中期开始， 年接下来的两个将以每12个月一个的速度分阶段进行。第四场比赛将于开始 从第四年开始到第五年结束。这个为期18个月的项目将于年中开始 第三，一年的项目，在第五年开始。与核心1临床研究平行 将对核心1和2原型器械、试剂和质控材料进行评价 为了提高可靠性，一系列指定的POC系统逐步准备进行实地试验。 我们还将征求POC连接建议，以便为 在第四年和第五年缩短特别探索期（18个月、12个月）。这些 连通性项目可能包括早期成功的探索性项目的延续， 为了使原型完全能够用于POC的医学解释和跟踪， 在救援和灾难中的测试结果。

Core 2. Plan for Identifying Collaborative Exploratory Projects Timeline for Exploratory POCT Technology Projects. Core 2 will produce new pathogen detection technologies consistent with the Core 3 theme of critical-emergencvdisaster care. Core 2 includes a total of six exploratory projects: a) four projects each two years in duration, b) one eighteen-month project, and c) one one-year project. The first round of Core 2 awards will be announced early in year one. The first project will start 1 April 2008. The first of four Core 2 projects, which begins in the middle of year one, will continue two years. The next two will be phased in at a rate of one per twelve months. The fourth will begin at the start of year four and end at the end of year five. The eighteen-month project will begin midyear three, and the one-year project, at the beginning of year five. In parallel with Core 1 clinical testing, Core 1 and 2 prototype devices, reagents, and quality control materials will be evaluated for robustness, and a designated line of POC systems progressively readied for field trails. We also will solicit POC connectivity proposals for successful robust prototypes for the shorter special exploratory periods (18 months, 12 months) in years four and five. These connectivity projects may include continuations of earlier successful exploratory projects in order to make the prototypes fully field enabled for medical interpretation and tracking of POC test results during rescue and disaster.