Circuit Training and Motivational Interviewing to Reduce Type 2 Diabetes in Youth

描述(由申请人提供)： Jaimie Davis在德克萨斯大学奥斯汀分校获得营养学博士学位，并在南加州大学预防医学系担任博士后研究员两年多一点。Davis博士近期的职业目标是：1)接受进一步培训，成为竞争同行评议资助，特别是R01资助金的独立调查员；2)获得运动生理学各方面的知识，包括运动干预措施的设计和实施，以及运动测试和解释；3)接受有关如何使用、整合和评分激励访谈的进一步培训，以促进体力活动行为的改善；4)研究通过运动干预降低代谢风险因素的机制；以及5)教育和指导本科生和研究生，使他们为将来从事预防和治疗儿童肥胖症和2型糖尿病做好准备。我的整个长期职业目标是开发和实施新颖、有效和可持续的干预措施，这些干预措施可以在高危少数群体社区环境中翻译和提供。我的培训活动将包括：1)直接指导Michael Goran、Leslie Bernstein、Donna Spruijt-Metz和Todd Schroeder，以及与Kathryn Schmitz和Teresa Moyer合作；2)参加培训会议和研讨会，以获得完成本研究所需的技能和知识；以及3)在南加州大学进行正式课程工作，以更好地了解运动生理学、脂肪分布和行为理论。拟议研究项目的总体目标是检查为期16周的巡回训练(力量训练有氧活动)计划的效果，包括使用激励性访谈的行为部分和不包括行为部分，在45名超重的拉丁裔青春期女孩(14-18岁)中减少肥胖和2型糖尿病风险因素。这项为期16周的随机对照研究将考察以下3个干预组对胰岛素动力学、脂肪组成和分布以及习惯性和随意体力活动的增量影响：1)对照组(延迟干预)，2)巡回训练组(每周2次)，或3)巡回训练动机访谈组(每周2次CT，每周1次)。受试者将接受临床测试，以评估代谢和生理结果，并接受直接观察，以评估干预前后的随意体力活动。 关联性。这项研究将为超重的拉丁裔青春期女性开发和实施独特的巡回训练(力量训练和心血管锻炼)计划，包括和不包括激励性访谈行为部分，旨在减少肥胖和2型糖尿病的风险因素。这项研究的结果将有助于在社区环境中创建更广泛、更多组成部分和持续的干预措施，以减少高危少数群体社区的肥胖和代谢性疾病。

DESCRIPTION (provided by applicant): Jaimie Davis received her doctorate in Nutritional Sciences from the University of Texas at Austin and has worked as a Postdoctoral Fellow for just over 2 years in the Department of Preventive Medicine at the University of Southern California. Dr. Davis's immediate career goals are to 1) receive further training to become an independent investigator to compete for peer reviewed funding, specifically R01 grants; 2) gain knowledge in various aspects of exercise physiology including the design and implementation of exercise interventions, and exercise testing and interpretation; 3) receive further training on how to use, integrate, and score Motivational Interviewing to foster improvements in physical activity behaviors; 4) investigate mechanisms that decrease metabolic risk factors with exercise interventions; and 5) educate and mentor undergraduate and graduate students in preparing them for careers in prevention and treatment of childhood obesity and type 2 diabetes. My overall long-term career goal is to develop and implement novel, effective and sustainable interventions that can be translated and delivered in high-risk minority, community settings. My training activities will involve: 1) direct mentorship of Michael Goran, Leslie Bernstein, Donna Spruijt- Metz, and Todd Schroeder and collaboration with Kathryn Schmitz and Teresa Moyer; 2) attending training conferences and seminars to gain the skills and knowledge needed to complete this study; and 3) formal coursework at USC to better understand exercise physiology, fat distribution and behavioral theories. The overall goal of the proposed research project is to examine the effects of a 16-week circuit-training (strength training + aerobic activities) program, with and without a behavioral component utilizing motivational interviewing, on decreasing obesity and type 2 diabetes risk factors in 45 overweight Latina adolescent girls (14-18 years of age). This 16-week randomized control study will examine the incremental effects of the following 3 intervention groups on insulin dynamics, fat composition and distribution, and habitual and ad libitum physical activity: 1) Control group (delayed intervention), 2) Circuit training group (2 times per week), or 3) Circuit training + Motivational Interviewing group (2 times per week of CT + weekly Ml sessions). Subjects will undergo clinical testing to assess metabolic and physiological outcomes and undergo direct observations to assess ad libitum physical activity before and after intervention. Relevance. This study will develop and implement a unique circuit training (strength training + cardiovascular exercise) program, with and without a motivational interviewing behavioral component, for overweight Latina adolescent females designed to reduce obesity and type 2 diabetes risk factors. Findings from this study will help create more wide scale, multi-component, and sustaining interventions in community settings targeting obesity and metabolic disease reduction in high-risk minority communities.