PROTEOMIC ANALYSIS OF BLOOD: ZN-ALPHA-2-GLYCOPROTEIN AS A BIOMARKER FOR CACHE

血液蛋白质组分析：ZN-ALPHA-2-糖蛋白作为缓存生物标志物

• 批准号: 7719594
• 负责人: BRENT M EGAN
• 金额: $ 0.23万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-05-01 至 2009-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7719594
• 关键词: Biological Markers; Blood; Cachexia; Computer Retrieval of Information on Scientific Projects Database; Condition; Disease; Funding; Grant; Institution; Kidney; Kidney Diseases; Measures; Proteins; Proteomics; Purpose; Renal function; Research; Research Personnel; Resources; Risk; Source; Tissues; United States National Institutes of Health; Zn-alpha-2-glycoprotein; wasting

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to find proteins in the blood that can be used to indicate disease. Subjects are being asked to participate in this study because they may have a condition that can be identified by the proteins in your blood. Specifically, people who have conditions that effect their kidneys may be at risk of developing cachexia, a wasting of body tissue, as the function of the kidneys decreases. Zn-alpha-2-glycoprotein is a protein that builds up in the blood of people with kidney disease and by measuring this protein researchers may be able to determine the extent of cachexia that occurs.

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这项研究的目的是寻找血液中可用于指示疾病的蛋白质。受试者被要求参与这项研究，因为他们可能患有可以通过你血液中的蛋白质识别的疾病。具体地说，患有影响肾脏的疾病的人可能会有患恶病质的风险，这是一种身体组织的浪费，随着肾脏功能的下降。锌-α-2-糖蛋白是一种在肾脏疾病患者血液中积聚的蛋白质，通过测量这种蛋白质，研究人员可能能够确定发生恶病质的程度。