CRYOTHERAPY FOR CHRONIC VENOUS DISORDERS: A PILOT

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目及 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本初步研究将在两组纵向研究中使用形成性方案开发方法，受试者被随机分配到治疗组或对照组，以评价慢性静脉疾病的冷冻治疗干预（n=30）。研究人员假设，冷却皮肤可以改善微循环，减少腿部疼痛，提高研究组的生活质量。在试点研究中，他们的目的是评估在研究组中招募，教育和管理这种新疗法的可行性，评估结果措施和估计进一步研究的样本量，并评估初步结果数据。治疗包括四周的日常凝胶包裹下肢30分钟。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This pilot study will use formative protocol development methods in a two-group longitudinal study with subjects randomly assigned to a treatment or control group to evaluate cryotherapy intervention (n=30) in chronic venous disease. The investigators hypothesize that cooling the skin improves microcirculation and will reduce leg pain and improve quality of life in the study group. In the pilot study they aim to assess the feasibility of recruiting, educating and administering this novel therapy in the study group, assess outcome measures and estimate sample size for further studies, and assess preliminary outcome data. Treatment involves four weeks of daily gel wraps on the lower extremity for 30 minutes.