CRYOTHERAPY FOR CHRONIC VENOUS DISORDERS: A PILOT

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这项先导性研究将在一项两组纵向研究中使用形成性方案开发方法，将受试者随机分配到一个治疗组或对照组，以评估冷冻治疗对慢性静脉疾病的干预(n=30)。研究人员假设，在研究组中，冷却皮肤可以改善微循环，减少腿部疼痛，提高生活质量。在试点研究中，他们的目标是评估在研究组中招募、教育和实施这种新疗法的可行性，评估结果衡量标准和估计进一步研究的样本量，并评估初步结果数据。治疗包括每天在腿部进行为期4周的凝胶包裹，每次30分钟。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This pilot study will use formative protocol development methods in a two-group longitudinal study with subjects randomly assigned to a treatment or control group to evaluate cryotherapy intervention (n=30) in chronic venous disease. The investigators hypothesize that cooling the skin improves microcirculation and will reduce leg pain and improve quality of life in the study group. In the pilot study they aim to assess the feasibility of recruiting, educating and administering this novel therapy in the study group, assess outcome measures and estimate sample size for further studies, and assess preliminary outcome data. Treatment involves four weeks of daily gel wraps on the lower extremity for 30 minutes.