CLINICAL TRIAL: PHYSIOLOGIC EFFECTS OF IGF-I IN ADOLESCENTS WITH ANOREXIA NERVOS

临床试验：IGF-I 对神经性厌食症青少年的生理影响

• 批准号: 7731288
• 负责人: Madhusmita Misra
• 金额: $ 0.39万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-04-01 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7731288
• 关键词: Acute; Adolescent; Anorexia; Anorexia Nervosa; Bone Density; Clinical Trials; Computer Retrieval of Information on Scientific Projects Database; Elderly; Female Adolescents; Fracture; Funding; Goals; Grant; Hormones; Institution; Insulin-Like Growth Factor I; Maintenance; Physiological; Research; Research Personnel; Resources; Risk; Skeletal system; Source; United States National Institutes of Health; bone; bone metabolism

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Adolescents with anorexia nervosa (AN) are at high risk for low bone mineral density, with implications for peak bone mass and fracture risk in later life. They are also deficient in insulin-like growth factor I (IGF-I), a hormone very important for the maintenance of skeletal integrity. Deficiency of IGF-I may contribute to the severe osteopenia seen in AN. The goal of this proposal is to investigate the acute effects of rhIGF-I on bone metabolism in adolescent girls with AN.

这个子项目是众多研究子项目之一