CLINICAL TRIAL: ESZOPICLONE ON SLEEP AND LEARNING

点击翻译按钮获取中文摘要

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Cognitive deficits are a persistent and relatively treatment-resistant feature of schizophrenia. The seeming generality of neurocognitive deficits in schizophrenia leaves one searching for a parsimonious explanation - a deficiency in a basic process that may be required in common by many cognitive functions.The goals of this study are to explore the basis of this sleep-dependent failure of consolidation and to determine whether sleep and cognition are improved by eszopiclone.