EFFECTS OF ROZEREM" (RAMELTEON - 8 MG) ON THERMOREGULATORY PHYSIOLOGY AND DAYTI

ROZEREM”（RAMELTEON - 8 MG）对体温调节生理学和 DAYTI 的影响

• 批准号: 7719563
• 负责人: KENNETH C WRIGHT
• 金额: $ 0.09万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-04-01 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7719563
• 关键词: Adult; Body Temperature; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Heat Losses; Hormones; Institution; Jet Lag Syndrome; Lead; Melatonin; Physiology; Reporting; Research; Research Personnel; Resources; Skin Temperature; Sleep; Sleep Disorders; Source; Temperature; Testing; Time; United States Food and Drug Administration; United States National Institutes of Health; falls; improved; novel; shift work; sleeping pill

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. A reduction in body temperature and an increase skin temperature (heat loss) are reported to be associated with faster times to fall asleep and possibly better sleep quality. We propose to test the influence of a new FDA approved sleeping pill called Ramelteon on temperature and daytime sleep in healthy adults. Ramelteon is a novel sleeping pill that is similar to the naturally occurring hormone melatonin produced by the body at night. The results from the current study may help us better understand how Ramelteon improves sleep and may lead to new treatments for sleep disorders such as those associated with shift work and jet lag.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 据报道，体温降低和皮肤温度增加（热量损失）与更快入睡时间和可能更好的睡眠质量有关。我们建议测试一种新的FDA批准的安眠药Ramelteon对健康成年人的温度和白天睡眠的影响。 Ramelteon是一种新型安眠药，类似于人体在夜间产生的自然产生的褪黑激素。 目前研究的结果可能有助于我们更好地了解Ramelteon如何改善睡眠，并可能导致睡眠障碍的新治疗方法，例如与轮班工作和时差有关的睡眠障碍。