SEX DIFFERENCES IN PHARMACOKINETICS OF LOPINAVIR/RITONAVIR AMONG HIV-1 INFECT

HIV-1 感染者中洛匹那韦/利托那韦药代动力学的性别差异

• 批准号: 7717997
• 负责人: Judith S. Currier
• 金额: $ 1.23万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-12-01 至 2008-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7717997
• 关键词: Area; Computer Retrieval of Information on Scientific Projects Database; Dose; Drug Kinetics; Funding; Grant; Institution; Lopinavir; Lopinavir/Ritonavir; Research; Research Personnel; Resources; Sex Characteristics; Source; Time; United States National Institutes of Health; Woman; men

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. SPECIFIC AIMS To compare the pharmacokinetic (PK) parameter, area under the concentration-time curve (AUC) of Lopinavir (LPV) between HIV-1-infected men and women currently receiving similar doses of Lopinavir/ritonavir (LPV/RTV).

这个子项目是许多利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 具体目标 比较目前接受相似剂量洛匹那韦/利托那韦（LPV/RTV）的HIV-1感染男性和女性的药代动力学（PK）参数、洛匹那韦（LPV）的浓度-时间曲线下面积（AUC）。