Activity and Participation in Ambulatory Cerebral Palsy

动态脑瘫的活动和参与

• 批准号: 7643499
• 负责人: KRISTIE F BJORNSON
• 金额: $ 12.74万
• 依托单位: SEATTLE CHILDREN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-06-01 至 2014-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7643499
• 关键词: Address; Adipose tissue; Adolescent; Adult; Advisory Committees; Age; Algorithms; Ankle; Award; Biomechanics; Body Composition; Body Size; Body Weight; Braces-Orthopedic appliances; Cerebral Palsy; Child; Childhood; Classification; Clinic; Clinic Activity; Clinical Research; Clinical Trials; Cross-Sectional Studies; Crossover Design; Data; Demographic Factors; Development; Development Plans; Doctor of Philosophy; Education; Effectiveness; Energy Metabolism; Fatty acid glycerol esters; Foundations; Friends; Gait; Genetic Crossing Over; Goals; Grant; Guidelines; Habits; Health; Height; Hip region structure; Housing; Impairment; International; Intervention; Intervention Studies; Knee; Knowledge; Language; Leadership; Length; Life; Life Experience; Life Style; Little' s Disease; Living Wills; Longevity; Measurement; Measures; Mentors; Methodology; Methods; Modeling; Motor; Movement; Nursery Schools; Orthotic Devices; Outcome; Outcome Measure; Participant; Pattern; Pediatrics; Performance; Persons; Pharmaceutical Preparations; Physical activity; Play; Population Study; Principal Investigator; Publishing; Randomized; Recreation; Relative (related person); Reporting; Research; Research Institute; Research Personnel; Rotation; Running; Sampling; Schools; Solid; Structure; Testing; Toes; Training Programs; Triceps Brachii Muscle; Typology; Universities; Upper arm; Walking; Washington; Weight; Work; Writing; Youth; base; career; career development; cohort; design; disability; foot; improved; intervention program; medical schools; muscle strength; novel; orthotics; patient oriented; professor; programs; public health relevance; rehabilitation strategy; skills; social; standardize measure; two-dimensional

DESCRIPTION (provided by applicant): The candidate, Kristie Bjornson, PhD, PT, is a pediatric physical therapist and Assistant Professor of Pediatrics, University of Washington School of Medicine/Seattle Children's Research Institute. This award will establish her as an independent investigator in a patient-oriented clinical research program of interventions focused on improving the activity and social participation of persons with cerebral palsy (CP). This overarching goal will be accomplished through a five-year program of training, mentoring and research with the following specific objectives: 1) Develop knowledge and skill in the measurement of body composition, energy expenditure, ambulatory and physical activity performance and social participation within the context of daily life. 2) Employ skills in a cross-sectional descriptive study testing the relationship of the ICF components. 3) Enhance understanding of orthotic prescription and biomechanics. 4) Develop methodology and pilot within a cross-sectional orthotic intervention study. 5) Expand knowledge of clinical trials methods, study management/leadership, grant development and scholarly writing. The candidate's sponsor is an established pediatric researcher and career mentor, while her co-sponsor and advisory committee represent clinical and research expertise directly related to the study population and career development plan. The research plan focuses first on defining the relationships of activity, participation (ICF) and body composition in a descriptive cross-sectional study of ambulatory children with CP. The extent outcomes at various levels of the ICF relate requires clarification in order for the ICF to be a useful framework for clinical research and practice. Secondarily, the ICF component relationships will be tested within a randomized cross-over clinical trial of solid ankle foot orthoses (SAFO) on daily ambulatory/physical activity performance and social participation on ambulatory children with cerebral palsy with novel ambulatory accelerometry measures. There are no published data defining the impact of SAFO on physical and ambulatory activity performance and participation in day to day life. This information will facilitate the development of a life span orthotic management algorithm for ambulatory persons with CP. Public Health Relevance: The PIs will explore the connection between what a child with cerebral palsy does physically during motor testing to what they 'actually' do during their day to day lives. The project will also test whether ankle braces help children with cerebral palsy do what they want to do when they want to do it. This information will be used to develop ankle bracing guidelines for persons with, cerebral palsy across the life span.

描述（由申请人提供）：候选人 Kristie Bjornson，博士，PT，是华盛顿大学医学院/西雅图儿童研究所的儿科物理治疗师和儿科助理教授。该奖项将使她成为一项以患者为导向的临床干预研究计划的独立研究者，该计划的重点是改善脑瘫（CP）患者的活动和社会参与。这一总体目标将通过为期五年的培训、指导和研究计划来实现，其具体目标如下： 1) 培养在日常生活中测量身体成分、能量消耗、流动和身体活动表现以及社会参与的知识和技能。 2) 在横断面描述性研究中运用技能来测试 ICF 组成部分的关系。 3) 增强对矫形处方和生物力学的理解。 4) 在横断面矫形干预研究中制定方法和试点。 5) 扩展临床试验方法、研究管理/领导、资助开发和学术写作的知识。候选人的发起人是一位资深的儿科研究员和职业导师，而她的共同发起人和咨询委员会则代表与研究人群和职业发展计划直接相关的临床和研究专业知识。该研究计划首先侧重于在一项针对患有脑瘫的流动儿童的描述性横断面研究中定义活动、参与 (ICF) 和身体成分的关系。为了使 ICF 成为临床研究和实践的有用框架，需要澄清 ICF 各个层面的结果的相关程度。其次，ICF 成分关系将在固体踝足矫形器 (SAFO) 的随机交叉临床试验中进行测试，该试验对脑瘫患者的日常步行/体力活动表现和社交参与进行测试，并采用新颖的动态加速度测量方法。目前还没有公开的数据来定义 SAFO 对身体和步行活动表现以及日常生活参与的影响。这些信息将有助于开发针对脑瘫患者的可卧床矫形器管理算法。 公共健康相关性：PI 将探讨脑瘫儿童在运动测试期间的身体行为与他们在日常生活中“实际”所做的事情之间的联系。该项目还将测试脚踝支架是否可以帮助脑瘫儿童在他们想做的时候做他们想做的事情。这些信息将用于为脑瘫患者制定一生中的脚踝支撑指南。