Cognitive Behavior Therapy for PTSD and Medical Unexplained Physical Symptoms (MU

针对创伤后应激障碍 (PTSD) 和不明原因身体症状的认知行为疗法 (MU

• 批准号: 7589016
• 负责人: Carlos I Perez Benitez
• 金额: $ 5.23万
• 依托单位: BROWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-01-12 至 2009-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7589016
• 关键词: Address; Behavior; Behavior Therapy; Behavioral; Belief; Case Study; Chronic; Clinical; Clinical Trials; Cognitive; Comorbidity; Competence; Data; Diagnosis; Disadvantaged; Disease; Ethical Issues; Ethnic group; Exhibits; General Population; Goals; Grant; Guidelines; Healthcare; Hispanics; Instruction; International; Intervention; K-Series Research Career Programs; Knowledge; Latina; Latino; Manuals; Manuscripts; Medical; Mental Health; Mental disorders; Mentored Patient-Oriented Research Career Development Award; Mentors; Modality; Occupational; Participant; Patients; Pilot Projects; Population; Population Research; Post-Traumatic Stress Disorders; Preparation; Primary Health Care; Publishing; Randomized; Randomized Clinical Trials; Randomized Controlled Trials; Relative (related person); Reporting; Research; Research Ethics; Research Proposals; Sampling; Scientist; Societies; Somatization Disorder; Stigmata; Stress; Symptoms; Testing; Training; Trauma; Treatment outcome; Underrepresented Minority; United States; Writing; cognitive behavior therapy; depressive symptoms; design; efficacy testing; experience; follow up assessment; health care service utilization; help-seeking behavior; improved; insight; neglect; novel; patient oriented; primary care setting; psychosocial; skills; social; social stigma; treatment as usual

DESCRIPTION (provided by applicant): This application is the last resubmission to request a Mentored Patient-Oriented Research Career Development Award (K-23) that will provide me with necessary training to become an independent research scientist with expertise in developing and evaluating culturally competent cognitive behavioral treatment for Latino patients with posttraumatic stress disorder (PTSD) and co-occurring Medical Unexplained Physical Symptoms (MUPS). Both PTSD and MUPS are common, debilitating, and chronic psychological disorders that are associated with impaired social and occupational functioning. No treatment, to date, has been developed or tested to treat both groups of symptoms despite research and clinical evidence suggesting that these two groups of symptoms often co-occur as a result of trauma and that patients who suffer from trauma and develop PTSD are more likely to experience MUPS than those who do not have PTSD diagnoses. Latina/os report higher levels of trauma exposure, PTSD, and MUPS relative to the general population. They have been systematically neglected from treatment studies, especially treatment for PTSD, are less likely to access or engage in mental health care. My initial goal is to adapt and integrate existing cognitive behavioral treatments for PTSD and for MUPS and to collect preliminary data on the feasibility, acceptability, and efficacy of the adapted treatment. My training goals are 1) to advance my skills in designing and implementing randomized clinical trials in order to adapt treatment modalities, develop new treatment, and test established treatment for PTSD with comorbid MUPS; 2) continue enhancing my knowledge in phenomenology and developing skills in assessment of PTSD and somatization disorder; 3) extend competence in conducting treatment research with Latino populations in primary care; 4) become a certified cognitive behavioral therapist that will allow me to supervise therapists for large clinical trials; 5) receive training in research ethics, including ethical issues conducting research with participants who come from disadvantaged backgrounds; and 6) improve my grant-writing and manuscript preparation skills. RELEVANCE (See instructions): Despite the increasing numbers of Latinos in the United States, there is a dearth of substantial clinical knowledge about culturally competent treatments for Latino patients with mental disorders. They report higher levels of PTSD, and Medical Unexplained Physical Symptoms relative to the general population. This project will provide a novel treatment to reduce debilitating disorders and holds promise for providing insight into the socio-cultural factors associated with treatment outcomes among underserved minorities.

描述（由申请人提供）：本申请是申请指导性患者导向研究职业发展奖 (K-23) 的最后一次重新提交，该奖将为我提供必要的培训，使我成为一名独立研究科学家，具有为患有创伤后应激障碍 (PTSD) 和同时出现的医学原因不明的身体症状 (MUPS) 的拉丁裔患者开发和评估文化上合格的认知行为治疗的专业知识。 PTSD 和 MUPS 都是常见的、使人衰弱的慢性心理疾病，与社会和职业功能受损有关。迄今为止，尚未开发或测试治疗这两组症状的治疗方法，尽管研究和临床证据表明这两类症状经常因创伤而同时出现，并且遭受创伤并发展为 PTSD 的患者比没有诊断为 PTSD 的患者更有可能经历 MUPS。相对于一般人群，拉丁裔/其他群体报告的创伤暴露、创伤后应激障碍 (PTSD) 和 MUPS 水平较高。他们在治疗研究中被系统性地忽视，尤其是创伤后应激障碍（PTSD）的治疗，他们不太可能获得或参与心理保健。我的最初目标是调整和整合现有的针对 PTSD 和 MUPS 的认知行为治疗，并收集有关调整后的治疗的可行性、可接受性和有效性的初步数据。我的培训目标是 1) 提高设计和实施随机临床试验的技能，以便调整治疗方式、开发新的治疗方法并测试针对合并 MUPS 的 PTSD 的既定治疗方法； 2）继续增强我的现象学知识并发展评估创伤后应激障碍和躯体化障碍的技能； 3) 扩大在初级保健中对拉丁裔人群进行治疗研究的能力； 4）成为一名经过认证的认知行为治疗师，这将使我能够监督治疗师进行大型临床试验； 5）接受研究伦理方面的培训，包括与来自弱势背景的参与者进行研究的伦理问题； 6) 提高我的资助写作和稿件准备技能。相关性（参见说明）：尽管美国的拉丁裔人数不断增加，但对于拉丁裔精神障碍患者的文化上有效的治疗方法仍缺乏大量的临床知识。他们报告说，与一般人群相比，他们的创伤后应激障碍（PTSD）和不明原因的身体症状的发生率更高。该项目将提供一种新的治疗方法来减少衰弱性疾病，并有望深入了解与服务不足的少数群体治疗结果相关的社会文化因素。