NONALCOHOLIC FATTY LIVER DISEASE (NAFLD) DATABASE

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这是一项多中心观察性第三阶段研究，每个部位有200名确诊或疑似非酒精性脂肪性肝病(NAFLD)或隐源性肝硬变的患者。本研究的目的是：a)研究NAFLD的病因、自然病程、诊断、治疗和预防；b)建立包含NAFLD患者肝组织、血清、血浆、DNA和细胞系的标本库；c)为NAFLD的发病机制、自然病程和治疗的辅助研究提供资源。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This is a multi-center observational phase 3 study of 200 patients per site with definite or suspected nonalcoholic fatty liver disease (NAFLD) or cryptogenic cirrhosis. This study will aim to: a) investigate the etiology, natural history, diagnosis, treatment and prevention of NAFLD, b) develop a specimen bank comprising liver tissue, serum, plasma, DNA, and cell lines obtained from NAFLD patients and c) provide a resource for ancillary studies of the pathogenesis, natural history, and treatment of NAFLD.