ENDOCRINE DYSFUNCTION AND GROWTH HORMONE DEFICIENCY IN CHILDREN WITH ONH

ONH 儿童的内分泌功能障碍和生长激素缺乏

• 批准号: 7603961
• 负责人: MARK BORCHERT
• 金额: $ 1.36万
• 依托单位: UNIVERSITY OF SOUTHERN CALIFORNIA
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-12-01 至 2007-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7603961
• 关键词: Child; Computer Retrieval of Information on Scientific Projects Database; Development; Diagnosis; Endocrine; Functional disorder; Funding; Grant; Growth; Institution; Numbers; Optic Nerve; Outcome; Placebo Control; Purpose; Randomized; Research; Research Personnel; Resources; Somatotropin; Source; United States National Institutes of Health; growth hormone deficiency

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to study endocrinopathies in children diagnosed with optic nerve hypoplasia (ONH). The proposed study will be the first to specifically evaluate a large number of ONH children for endocrinological and growth outcomes, and the impact of growth hormone treatment on physical development. Subjects will be randomized to treatment with growth hormone vs observation only (no placebo control) and followed for two years for growth outcomes.

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 本研究的目的是研究诊断为视神经发育不良(ONH)的儿童的内分泌疾病。这项拟议的研究将首次专门评估大量ONH儿童的内分泌和生长结果，以及生长激素治疗对身体发育的影响。受试者将随机接受生长激素治疗和单纯观察(没有安慰剂对照)，并跟踪观察两年的生长结果。