CLINICAL RISK FACTORS IN OPTIC NERVE HYPOPLASIA

视神经发育不全的临床危险因素

• 批准号: 7368233
• 负责人: MARK BORCHERT
• 金额: $ 11.76万
• 依托单位: UNIVERSITY OF SOUTHERN CALIFORNIA
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-12-01 至 2006-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7368233
• 关键词: CLINICAL; RISK; FACTORS; OPTIC; NERVE

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Optic nerve hypoplasia (ONH), congenital underdevelopment of one or both optic nerves, was once thought to be rare but is now recognized as a major etiology of subnormal vision in children and is a leading cause of congenital blindness at CHLA. This study is designed to provide preliminary data about the factors that may be involved in the formation of ONH prior to birth. It is also designed to correlate those factors with the severity of the disease and its associated medical conditions.

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。视神经发育不全（ONH），先天性单侧或双侧视神经发育不全，曾经被认为是罕见的，但现在被认为是儿童视力不正常的主要病因，也是CHLA先天性失明的主要原因。本研究的目的是提供初步数据的因素，可能涉及ONH的形成之前出生前。它还旨在将这些因素与疾病的严重程度及其相关医疗条件联系起来。