Synapse Neurobiology Training Program

描述(由申请人提供)： 多学科方法可能比生物医学研究的大多数其他领域更能推动神经科学的进步。因此，下一代研究神经科学家必须具备多方面的技能，才能过渡到成功的独立职业生涯，并对该领域做出有意义的贡献。为了迎接这一挑战，我们在塔夫茨大学医学院提出了一个新的博士前Synapse神经生物学培训计划(SNTP)，该计划将在突触功能领域为4名学员提供深入的、多学科的研究教育--突触功能是塔夫茨神经科学学院的一个特别强项。突触构成神经系统功能的基础，突触的研究可以说是现代神经生物学中最交叉的领域之一。因此，SNTP培训计划包括几种机制，将受训人员定位为领先的神经科学家，在传统学科之间开展工作： 每名学员将由两名SNTP教职员工共同指导，他们在不同但互补的领域提供培训。 通过在成像、生物信息学、电生理学和动物行为方法方面的补贴一对一培训(通过NINDS资助的塔夫茨神经科学研究中心的核心设施和博士级别的管理人员提供)，SNTP学员将获得有效和有影响力的多学科方法所需的最先进的工具和培训。 创新的量化技能和技术课程和个性化的培训计划将进一步帮助每个SNTP学员掌握必要的技能，以实现他/她的研究职业目标。 与来访演讲者进行个人互动的频繁机会将为SNTP学员提供进一步接触新方法和想法以及建议和指导的机会。

DESCRIPTION (provided by applicant): Multidisciplinary approaches drive progress in the neurosciences perhaps more than in most other areas of biomedical research. The next generation of research neuroscientists, therefore, must be equipped with a multi-faceted skill set if they are to transition to successful independent careers and contribute meaningfully to the field. To meet this challenge, we propose a new predoctoral Synapse Neurobiology Training Program (SNTP) at Tufts University School of Medicine that will provide in-depth, multidisciplinary research education of 4 trainees in the area of synaptic function-a particular strength of the Tufts neuroscience faculty. The synapse forms the foundation of nervous system function, and research on synapses is, arguably, one of the most interdisciplinary areas in modern neurobiology. The SNTP training plan, thus, includes several mechanisms that position trainees to become leading neuroscientists, working at the interface between traditional disciplines: Each trainee will be co-mentored by two SNTP faculty members who provide training in distinct yet complementary areas. Through subsidized, one-on-one training in imaging, bioinformatics, electrophysiology, and animal behavior methods (provided via the core facilities and PhD-level Managers in the NINDS-funded Center for Neuroscience Research at Tufts), SNTP trainees will acquire the state-of-the-art tools and training required for an effective and influential multidisciplinary approach. Innovative quantitative skills and techniques courses and individualized training plans will further aid each SNTP trainee in mastering the necessary skills to accomplish his/her research career goals. Frequent opportunities for individual interactions with visiting speakers will provide SNTP trainees with further exposure to new methodologies and ideas as well as advice and guidance.