Synapse Neurobiology Training Program

描述（由申请人提供）： 多学科方法推动神经科学的进步可能超过生物医学研究的大多数其他领域。因此，下一代研究神经科学家必须具备多方面的技能，如果他们要过渡到成功的独立职业生涯，并为该领域做出有意义的贡献。为了迎接这一挑战，我们提出了一个新的博士前突触神经生物学培训计划（SNTP）在塔夫茨大学医学院，将提供深入的，多学科的研究教育，4名学员在该地区的突触功能塔夫茨神经科学教师的一个特殊优势。突触是神经系统功能的基础，对突触的研究可以说是现代神经生物学中最具跨学科性的领域之一。因此，SNTP培训计划包括几个机制，使受训者成为领先的神经科学家，在传统学科之间的接口工作： 每位学员将由两名SNTP教师共同指导，他们在不同但互补的领域提供培训。 通过在成像，生物信息学，电生理学和动物行为方法的补贴，一对一的培训（通过核心设施和博士级管理人员在NINDS资助的塔夫茨神经科学研究中心提供），SNTP学员将获得国家的最先进的工具和培训所需的有效和有影响力的多学科方法。 创新的定量技能和技术课程以及个性化的培训计划将进一步帮助每个SNTP学员掌握必要的技能，以实现他/她的研究职业目标。 与来访演讲者进行个人互动的频繁机会将为SNTP学员提供进一步接触新方法和想法以及建议和指导的机会。

DESCRIPTION (provided by applicant): Multidisciplinary approaches drive progress in the neurosciences perhaps more than in most other areas of biomedical research. The next generation of research neuroscientists, therefore, must be equipped with a multi-faceted skill set if they are to transition to successful independent careers and contribute meaningfully to the field. To meet this challenge, we propose a new predoctoral Synapse Neurobiology Training Program (SNTP) at Tufts University School of Medicine that will provide in-depth, multidisciplinary research education of 4 trainees in the area of synaptic function-a particular strength of the Tufts neuroscience faculty. The synapse forms the foundation of nervous system function, and research on synapses is, arguably, one of the most interdisciplinary areas in modern neurobiology. The SNTP training plan, thus, includes several mechanisms that position trainees to become leading neuroscientists, working at the interface between traditional disciplines: Each trainee will be co-mentored by two SNTP faculty members who provide training in distinct yet complementary areas. Through subsidized, one-on-one training in imaging, bioinformatics, electrophysiology, and animal behavior methods (provided via the core facilities and PhD-level Managers in the NINDS-funded Center for Neuroscience Research at Tufts), SNTP trainees will acquire the state-of-the-art tools and training required for an effective and influential multidisciplinary approach. Innovative quantitative skills and techniques courses and individualized training plans will further aid each SNTP trainee in mastering the necessary skills to accomplish his/her research career goals. Frequent opportunities for individual interactions with visiting speakers will provide SNTP trainees with further exposure to new methodologies and ideas as well as advice and guidance.