Permanent 100% Antimicrobial Medical Plastic

永久%20100%%20抗菌%20医用%20塑料

• 批准号: 8326570
• 负责人: Joel L Williams
• 金额: $ 51.13万
• 依托单位: BRIGHTON DEVELOPMENT, LLC
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-29 至 2014-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8326570
• 关键词: Accounting; Affect; Age; Age-Years; Area; Caring; Communities; Community Healthcare; Contact Dermatitis; Data; Development; Dose; Engineering; Environment; Expenditure; Feasibility Studies; Film; Formaldehyde; Frequencies; Gamma Rays; Goals; Growth; Handwashing; Health care facility; Healthcare; Healthcare Industry; Hospitals; Hour; Human; Hygiene; Infection; Intensive Care Units; Legal patent; Life; Measures; Medical; Methods; Nosocomial Infections; Oxides; Patients; Patients' Rooms; Phase; Plastics; Property; Pseudomonas aeruginosa; Safety; Shipping; Ships; Simulate; Small Business Innovation Research Grant; Soaps; Staphylococcus aureus; Surface; Technology; Temperature; Testing; Touch sensation; United States; United States National Institutes of Health; Validation; Work; antimicrobial; base; carbene; care systems; combat; cost; delrin; dosage; hospital bed; innovation; irradiation; killings; microbial; microorganism; physical property; prevent; product development; statistics

DESCRIPTION (provided by applicant): PERMANENT 100% ANTIMICROBIAL MEDICAL PLASTIC Combating infections is one of the major goals of the entire medical community due to the exponential cost associated with care of an infected patient. Technology innovations to reduce infection brought about by cross-contamination of patients staying in healthcare facilities can have major impact to the medical community in terms of both dollars and human lives. Approximately 5% to 10% of all patients entering a hospital will contact some form of infection during their stay at the healthcare facility. It is estimated that hospitals spend over $30 billion annually and over 100,000 lives can be lost as a result of nosocomial infections. Statistics show that personal hygiene consisting mainly of hand washing with antimicrobial soaps does not occur frequently enough to prevent the $30 billion dollar expenditure that healthcare facilities endure on an annual basis. Unfortunately, medical products containing only 0.1-1.0% of leachable antimicrobial additives only provide temporary antimicrobial action because the biocidal agent can be easily removed by washing or wiping the surface of the medical product. Brighton Development has developed with NIH support a 100% permanent antimicrobial plastic that can be used in numerous medical products found in the healthcare community. In Phase II, we would like to focus on exploiting the feasibility of this discovery as a permanent 100% antimicrobial material and demonstrate its advantages in combating infection in the healthcare environment. Brighton Development will generate the required data to obtain registration of the 100% antimicrobial products with the EPA and subsequently provide these products to the healthcare community. The goals of this project are in alignment with one of NIH top priorities of HAI elimination (Healthcare-associated Infections) that has dramatic impact in terms of both dollars and human lives.

描述（由申请人提供）：由于与受感染患者的护理相关的指数成本，永久性100％抗菌药物塑料作用是整个医学界的主要目标之一。通过在医疗机构中留在医疗机构的患者交叉污染而导致感染的技术创新可能会对医疗界产生重大影响，从而对医疗界产生重大影响。所有进入医院的患者中，大约5％至10％将在医疗机构逗留期间与某种形式的感染联系。据估计，医院每年花费超过300亿美元，由于医院感染而导致的100,000多人可能会丧生。统计数据显示，主要由抗菌肥皂洗手的个人卫生频率不够频繁，无法防止医疗机构每年持续的300亿美元支出。不幸的是，仅包含0.1-1.0％的可渗透抗微生物添加剂的医疗产品仅提供临时抗菌作用，因为可以通过清洗或擦除医疗产品表面来轻松去除杀菌剂。 Brighton Development通过NIH支持了100％永久性抗菌塑料，可用于医疗保健社区中的许多医疗产品。在第二阶段，我们希望专注于利用这一发现作为永久100％抗菌材料的可行性，并证明了其在医疗保健环境中打击感染方面的优势。布莱顿开发将生成所需的数据，以获取与EPA的100％抗菌产品的注册，并随后向医疗保健社区提供这些产品。该项目的目标与NIH消除的最高重点之一（与医疗保健相关的感染）保持一致，该重点在美元和人类的生活方面都产生了巨大影响。