Unique Antimicrobial Catheter to Prevent Urinary Tract Infections
Unique Antimicrobial Catheter to Prevent Urinary Tract Infections
批准号:
8591127
负责人:
Joel L Williams
金额:
$18.29万
依托单位国家:
美国
项目类别:
财政年份:
2013
资助国家:
美国
项目状态:
已结题
起止时间:
2013-09-18 至 2015-08-30
关键词:
Anti-Bacterial AgentsAntibioticsCathetersCell SurvivalCessation of lifeDevelopmentDevicesDoseElastomersFDA approvedFeasibility StudiesFillerFormaldehydeGoalsHealth Care CostsHealth PrioritiesHealthcareHumanInfectionInfection preventionLength of StayLocal Anti-Infective AgentsManufactured MaterialsMeasurementMeasuresMechanicsMedicalMethenamineMoldsOxidesPatientsPhasePolymersProcessProduct PackagingPropertyServicesSilicon DioxideSilicone ElastomersSourceSterilizationSurfaceTechnologyTestingTimeUnited States National Institutes of HealthUrinary tractUrinary tract infectionantimicrobialantimicrobial drugbasecarbenecatheter associated UTIcontrolled releasecostdelrindepolymerizationdesigninnovationirradiationmanufacturing processmeltingmonomernovel strategiespathogenphysical propertypreventprototypepublic health relevanceresearch and developmentresponseurinary
中文摘要
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英文摘要
DESCRIPTION (provided by applicant): The goal of this Phase I effort is determine the feasibility of developing a unique antimicrobial catheter to reduce the instances of the most prevalent healthcare associated infection, Catheter-Associated Urinary Tract Infection (CAUTI). This research and development effort will be to develop a urinary catheter with inherent long lasting antiseptic properties to protect the patient and prevent infection. The proposed device is a new approach to antimicrobial catheters. It will use common Foley catheter designs and materials, with the addition of an additive to the elastomer to render the catheter antimicrobial. The additive replaces the silica reinforcing filler in the elastomer and is designed to give a long
lasting time release of antibacterial agent to the catheter surface. The catheter can be manufactured inexpensively with standard medical tubing manufacturing processes and materials, but will have the value-added property of antimicrobial activity. A durable and effective antimicrobial catheter that can prevent or reduce CAUTI will save millions of dollars in healthcare cost and thousands of lives annually.
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海外基金