Unique Antimicrobial Catheter to Prevent Urinary Tract Infections

描述（由申请人提供）：本I期工作的目标是确定开发一种独特的抗菌导管的可行性，以减少最普遍的医疗相关感染——导管相关性尿路感染（CAUTI）的发生。这项研究和开发工作将是开发一种具有固有持久防腐性能的导尿管，以保护患者并防止感染。所提出的装置是一种新的抗菌导管。它将使用常见的Foley导管设计和材料，并在弹性体中添加添加剂以使导管具有抗菌性。该添加剂取代了弹性体中的二氧化硅增强填料，并被设计为提供长

DESCRIPTION (provided by applicant): The goal of this Phase I effort is determine the feasibility of developing a unique antimicrobial catheter to reduce the instances of the most prevalent healthcare associated infection, Catheter-Associated Urinary Tract Infection (CAUTI). This research and development effort will be to develop a urinary catheter with inherent long lasting antiseptic properties to protect the patient and prevent infection. The proposed device is a new approach to antimicrobial catheters. It will use common Foley catheter designs and materials, with the addition of an additive to the elastomer to render the catheter antimicrobial. The additive replaces the silica reinforcing filler in the elastomer and is designed to give a long lasting time release of antibacterial agent to the catheter surface. The catheter can be manufactured inexpensively with standard medical tubing manufacturing processes and materials, but will have the value-added property of antimicrobial activity. A durable and effective antimicrobial catheter that can prevent or reduce CAUTI will save millions of dollars in healthcare cost and thousands of lives annually.