PERMANENT ANTIMICROBIAL MEDICAL PLASTIC

永久抗菌医用塑料

• 批准号: 7611872
• 负责人: Joel L Williams
• 金额: $ 10万
• 依托单位: BRIGHTON DEVELOPMENT, LLC
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-29 至 2010-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7611872
• 关键词: Accounting; Affect; Age-Years; Aspergillus niger; Communities; Community Healthcare; Condition; Development; Dose; Engineering; Environment; Expenditure; Feasibility Studies; Formaldehyde; Frequencies; Germ; Goals; Growth; Guidelines; Handwashing; Health care facility; Healthcare; Hospitals; Human; Hygiene; Infection; Life; Measures; Medical; Microbe; Nosocomial Infections; Organism; Patients; Phase; Plastics; Property; Pseudomonas aeruginosa; Public Health; Radiation; Reproduction spores; Screening procedure; Soaps; Staphylococcus aureus; Surface; Technology; Temperature; Testing; Touch sensation; antimicrobial; base; delrin; innovation; instrument; irradiation; killings; microbial; physical property; prevent; statistics; transmission process

DESCRIPTION (provided by applicant): Technology innovations to reduce infection brought about by cross- contamination of patients staying in healthcare facilities can have major significance to the medical community in terms of both dollars and human lives. Approximately 5% to 10% of all patients entering a hospital will contact some form of infection during their stay at the healthcare facility. It is estimated that hospitals spend over $5 billion annually and over 100,000 lives can be lost as a result of nosocomial infections. Statistics show that personal hygiene consisting mainly of hand washing with antimicrobial soaps does not occur frequently enough to prevent the $5 billion dollar expenditure that healthcare facilities endure on an annual basis. Unfortunately, medical products containing only 0.1-1.0% of leachable antimicrobial additives only provide temporary antimicrobial action because the biocidal agent can be easily removed by washing or wiping the surface of the medical product. Brighton Development has developed a 100% permanent antimicrobial plastic that can be used in numerous medical products found in the healthcare community. In Phase I, we would like to focus on exploiting the feasibility of this discovery as a permanent antimicrobial material and demonstrate its advantages in combating infection in the healthcare environment. PUBLIC HEALTH RELEVANCE: This application is aimed at developing a permanent antimicrobial medical plastic that can be used to reduce the billions of dollars spent annually by healthcare facilities to combat patient infections. Statistics show that the magnitude of this problem affects from 5-10% of all people entering the hospital and accounts for annual expenditures by the medical community of over 5 billion dollars even with documented frequencies of antimicrobial hand washing by hospital staff. A truly durable antimicrobial plastic material could find numerous uses in medical products throughout healthcare facilities.

描述（由申请人提供）：减少医疗机构中患者交叉污染所带来的感染的技术创新在金钱和人类生命方面对医学界具有重大意义。大约5%至10%的患者在住院期间会接触某种形式的感染。据估计，医院每年花费超过50亿美元，医院感染可能导致10万多人丧生。统计数据显示，主要包括用抗菌肥皂洗手的个人卫生并不经常发生，不足以防止医疗机构每年承受的50亿美元支出。不幸的是，仅含有0.1-1.0%的可浸出抗微生物添加剂的医疗产品仅提供暂时的抗微生物作用，因为杀生物剂可以通过洗涤或擦拭医疗产品的表面而容易地去除。Brighton Development开发了一种100%永久性抗菌塑料，可用于医疗保健领域的许多医疗产品。在第一阶段，我们希望专注于利用这一发现作为永久性抗菌材料的可行性，并展示其在医疗环境中对抗感染的优势。公共卫生关系：该应用旨在开发一种永久性抗菌医用塑料，可用于减少医疗机构每年用于对抗患者感染的数十亿美元。统计数据显示，该问题的严重程度影响到所有进入医院的人的5-10%，并且即使有记录的医院工作人员抗菌洗手的频率，医疗界的年度支出也超过50亿美元。一种真正耐用的抗菌塑料材料可以在整个医疗机构的医疗产品中找到许多用途。