DEVELOPMENT OF SOFTWARE FOR IMAGE ANALYSIS, DISPLAY, AND MODELING

图像分析、显示和建模软件的开发

• 批准号: 8362524
• 负责人: DAVID N MASTRONARDE
• 金额: $ 4.26万
• 依托单位: UNIVERSITY OF COLORADO
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8362524
• 关键词: Address; Cell physiology; Cellular Structures; Code; Computer software; Data Set; Development; Documentation; Excision; Funding; Generations; Grant; Image; Image Analysis; Linux; Methods; Modeling; National Center for Research Resources; Operating System; Principal Investigator; Research; Research Infrastructure; Resources; Roentgen Rays; Running; Source; Tomogram; United States National Institutes of Health; Work; charge coupled device camera; cost; graphical user interface; image reconstruction; programs; software development; tomography

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. We have continued development and support of the IMOD software package for tomographic reconstruction and image display, modeling, and analysis. Major milestones were the first release of the eTomo graphical interface for tomogram generation (described elsewhere) and the release of fully functional versions for Microsoft Windows and Macintosh OS X operating systems. Some significant functionality was added in the past year, including a program for automatic removal of X-rays from CCD camera images, the ability to bin down images when loading them into the 3dmod display and modeling program, and other changes to facilitate working with very large data sets. We developed a new method for providing parameter input to programs, to make it easier to run them manually or from other programs such as eTomo, to allow new options to be added to programs without breaking existing code and command files, and to centralize the specification and documentation of program options. About 15 Fortran programs have been converted to the new method. There were also major improvements in documentation: a guide to 3dmod was revised and greatly expanded to provide a comprehensive introduction to the program; a guide to tomography was thoroughly revised to describe how to work through eTomo; and a tutorial for building tomograms was also released, together with a complete dual-axis data set. With the release of versions for new platforms, downloads of the software are higher than ever. For the 2 weeks after the major version release in November 2003 plus 7 weeks in February/March 2003, there were downloads from 299 distinct IP addresses, of which 49% were for Windows, 25% for Linux, 21% for Macintosh, and 5% for SGI.

该子项目是利用资源的众多研究子项目之一 由 NIH/NCRR 资助的中心拨款提供。子项目的主要支持 并且子项目的主要研究者可能是由其他来源提供的， 包括其他 NIH 来源。 子项目可能列出的总成本 代表子项目使用的中心基础设施的估计数量， NCRR 赠款不直接向子项目或子项目工作人员提供资金。 我们持续开发和支持用于断层重建和图像显示、建模和分析的 IMOD 软件包。 主要里程碑是用于断层扫描生成的 eTomo 图形界面的首次发布（在别处描述）以及针对 Microsoft Windows 和 Macintosh OS X 操作系统的全功能版本的发布。 去年添加了一些重要的功能，包括自动从 CCD 相机图像中去除 X 射线的程序、将图像加载到 3dmod 显示和建模程序中时对图像进行分类的能力，以及便于处理非常大的数据集的其他更改。 我们开发了一种向程序提供参数输入的新方法，以便更轻松地手动运行它们或从 eTomo 等其他程序运行它们，允许在不破坏现有代码和命令文件的情况下将新选项添加​​到程序中，并集中程序选项的规范和文档。 大约 15 个 Fortran 程序已转换为新方法。 文档方面也有重大改进：修订并大幅扩展了 3dmod 指南，以提供对该程序的全面介绍；彻底修订了断层扫描指南，以描述如何通过 eTomo 进行工作；还发布了构建断层图的教程以及完整的双轴数据集。 随着新平台版本的发布，该软件的下载量比以往任何时候都高。 在 2003 年 11 月主要版本发布后的 2 周内以及 2003 年 2 月/3 月的 7 周内，有来自 299 个不同 IP 地址的下载，其中 49% 用于 Windows，25% 用于 Linux，21% 用于 Macintosh，5% 用于 SGI。