The role of ghrelin and NPY signaling in the regulation of energy homeostasis
The role of ghrelin and NPY signaling in the regulation of energy homeostasis
批准号:
8018448
负责人:
Heather Dungan Lemko
金额:
$4.76万
依托单位国家:
美国
项目类别:
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-09-15 至 2012-09-14
关键词:
AcuteBody WeightCardiovascular DiseasesCellsChronicDiabetes MellitusDietEatingEnergy MetabolismFatty acid glycerol estersGlucoseHomeostasisHormonesHyperglycemiaHyperphagiaInsulin ResistanceKnockout MiceLinkMediatingObesityOvernutritionPredispositionReceptor SignalingRegulationRoleSignal TransductionSomatotropinWeight GainWorkblood glucose regulationfeedingghrelinghrelin receptorglobal healthinsulin sensitivityreceptor expressionresearch studyrespiratoryrestoration
中文摘要
描述(由申请人提供):
肥胖已经成为一个全球性的健康问题,因为它与心血管疾病有关,
疾病、糖尿病、呼吸系统疾病等。这项提案中描述的工作将“通过研究促肥胖激素生长激素释放肽如何引发暴饮暴食、体重增加和高血糖,有助于我们理解肥胖和胰岛素抵抗的潜在机制。"
英文摘要
DESCRIPTION (provided by applicant):
Obesity has become a global health concern because it is linked to such conditions as cardiovascular
disease, diabetes, respiratory illness, and others. The work described in this proposal will "contribute to our understanding of the mechanisms underlying obesity and insulin resistance by examining how the pro-obesity hormone ghrelin triggers overeating, weight gain, and hyperglycemia."
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会议论文
The role of ghrelin and NPY signaling in the regulation of energy homeostasis
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批准号:8129579
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项目类别:
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资助金额:$4.97万
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财政年份:2009
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负责人:Heather Dungan Lemko
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依托单位:
The role of ghrelin and NPY signaling in the regulation of energy homeostasis
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批准号:7805888
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项目类别:
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资助金额:$4.52万
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财政年份:2009
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负责人:Heather Dungan Lemko
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依托单位:
海外基金