7th International Conference on Frontotemporal Dementias

描述（由申请人提供）：自1986年在瑞典隆德举行的第一届额颞叶痴呆国际会议以来，将参与额颞叶痴呆领域研究的科学家聚集在一起的活动和兴趣越来越多。这些会议的一个特点是其多学科性，这使得具有不同技术专门知识领域的科学家能够迅速扩大知识和传播思想。在同一时期，分子遗传学的快速发展和人类基因组计划的完成使得FTD研究的进展比前100年要快得多。在过去的二十年中，对痴呆症分子基础的研究已经导致对阿尔茨海默病和许多其他痴呆症的临床和神经病理学基础的理解。阿尔茨海默病和其他退行性痴呆之间的区别有时很难在临床上发现；然而，成像、遗传和其他生物标志物研究的日益复杂导致了这些疾病的新分类。1994年，随着FTD与17号染色体的联系的发现，一个重要的推动力出现了，并导致重新努力了解匹克病和其他形式额颞叶痴呆的生物学基础(9)。额颞叶痴呆，最近被称为额颞叶变性（FTLD），是一种临床、病理和基因多样化的疾病，共同构成65岁以下人群痴呆症的第二大常见原因。具体目标：1)为受邀演讲的初级教师提供学费和旅费补贴；2)为少数民族学生、教师或其他提交了海报摘要的专业卫生保健工作者提供学费和旅费补贴；3)为照顾受影响家庭成员的少数民族非专业护理人员提供学费和旅费补贴。已经成立了四个不同的委员会来协助筹备这次会议的各个方面。科学和护理委员会的成员包括当今FTD领域的许多主要研究人员。会议计划旨在为与会者提供一个了解与FTD相关的广泛主题的机会。本次会议的一个重点是纳入初级调查人员、少数民族和服务不足的人群。本申请寻求资金来帮助主要研究者实现这一目标。

DESCRIPTION (provided by applicant): Since the first international conference on frontotemporal dementias (FTD), which took place in Lund, Sweden in 1986, there has been increasing activity and interest in bringing together scientists involved in research in the field of FTD. A characteristic of these conferences has been their multidisciplinarity, which has allowed a rapid expansion of knowledge and dissemination of ideas among scientists with different areas of technical expertise. During the same period of time, the rapid developments in molecular genetics and the completion of the human genome project have allowed FTD research to progress much more rapidly than in the preceding 100 years. Over the past two decades, studies of the molecular basis of dementia have led to an understanding of the clinical and neuropathologic basis of Alzheimer disease and of numerous other dementias. The difference between Alzheimer disease and other degenerative dementias is, at times, difficult to detect clinically; however, the increased sophistication of imaging, genetic and other biomarker studies has led to the new classifications of these disorders. A major impetus occurred in 1994, with the discovery of a linkage of FTD to chromosome 17, and has led to a renewed effort to understand the biological basis of Pick disease and other forms of frontotemporal dementia (9). Frontotemporal dementia, more recently called frontotemporal lobar degeneration (FTLD), is a clinically, pathologically and genetically diverse group of disorders that together constitute the second most common cause of dementia in those younger than 65 years of age. Specific Aims: 1) Support tuition and travel stipends for junior faculty who have been invited to speak, 2) Support tuition and travel stipends for minority students, faculty or other professional health care workers who have submitted an abstract for a poster presentation, and 3) Support tuition and travel stipends for minority non-professional caregivers caring for an affected family member. Four different committees have been formed to aid in the various aspects of preparing for this conference. The scientific and caregiver committees' membership includes many of the leading researchers in the field of FTD today. The conference programs have been designed to offer attendees an opportunity to learn about a broad spectrum of topics related to FTD. A major point of emphasis for this conference is the inclusion of junior investigators and minorities and under-served populations. This application seeks funds to aid the principal investigator in this goal. PUBLIC HEALTH RELEVANCE: The purpose of this application is to request funds to support the 7th International Conference on Frontotemporal Dementias. This conference is a forum for research scientists, clinicians, and other health care professionals to share the latest information from each of their disciplines. In addition to highlighting the progress made in the various areas of research, this conference will provide an opportunity for non-professional caregivers to be exposed to new knowledge and to interact with researchers and other caregivers.