ROLE OF MU AGONIST EFFICACY IN OPIOID ENHANCEMENT OF COCAINE SELF-ADMINISTRATION

MU 激动剂功效在阿片类药物增强可卡因自我给药中的作用

• 批准号: 7958325
• 负责人: ROGER D SPEALMAN
• 金额: $ 1.27万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-05-01 至 2010-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7958325
• 关键词: Agonist; Cocaine; Cocaine Abuse; Computer Retrieval of Information on Scientific Projects Database; Dopamine Receptor; Funding; Grant; Institution; New England; Opioid; Primates; Research; Research Personnel; Resources; Role; Self Administration; Source; United States National Institutes of Health; base; receptor

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This project investigates the roles of specific opioid and dopamine receptor mechanisms in the dual abuse of cocaine and opioids to provide an objective framework for identifying receptor targets for the pharmacological management of speedball abuse.

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 本项目研究阿片和多巴胺受体的特定机制在可卡因和阿片类药物双重滥用中的作用，以提供一个客观的框架，为快速球滥用的药物管理确定受体靶标。