DOPAMINE D3 RECEPTOR LIGANDS FOR TREATMENT OF SUBSTANCE ABUSE

用于治疗药物滥用的多巴胺 D3 受体配体

• 批准号: 8357932
• 负责人: ROGER D SPEALMAN
• 金额: $ 1.38万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8357932
• 关键词: Agonist; Disease; Funding; Grant; Ligands; National Center for Research Resources; New England; Primates; Principal Investigator; Research; Research Infrastructure; Resources; Role; Source; United States National Institutes of Health; base; cost; dopamine D3 receptor; receptor; stimulant abuse; substance abuse treatment

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. This project investigates the role of dopamine D3 receptor mechanisms in stimulant abuse and the potential utility of D3 receptor antagonists and partial agonists for the treatment of substance abuse disorders.

该子项目是利用资源的众多研究子项目之一 由 NIH/NCRR 资助的中心拨款提供。子项目的主要支持 并且子项目的主要研究者可能是由其他来源提供的， 包括其他 NIH 来源。 子项目可能列出的总成本 代表子项目使用的中心基础设施的估计数量， NCRR 赠款不直接向子项目或子项目工作人员提供资金。 该项目研究多巴胺 D3 受体机制在兴奋剂滥用中的作用以及 D3 受体拮抗剂和部分激动剂在治疗药物滥用疾病中的潜在用途。