PHARMACOLOGICAL STRATEGIES FOR AUGMENTING EXTINCTION OF DRUG SEEKING

加强消除寻毒行为的药理学策略

• 批准号: 7958361
• 负责人: ROGER D SPEALMAN
• 金额: $ 1.27万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-05-01 至 2010-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7958361
• 关键词: Behavior; Cocaine; Computer Retrieval of Information on Scientific Projects Database; Cues; Development; Extinction (Psychology); Funding; Grant; Institution; New England; Pharmaceutical Preparations; Pharmacotherapy; Primates; Relapse; Research; Research Personnel; Resources; Self Administration; Source; United States National Institutes of Health; base; cognitive behavior therapy

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This project builds on advances in cognitive-behavioral therapy (cue-exposure/extinction therapy) in conjunction with pharmacotherapy to investigate the use of glycinergic drugs to accelerate extinction of cocaine-seeking behavior and to reduce relapse to cocaine self-administration. The approach serves as a transitional interface for development of effective pharmacological adjuncts to extinction therapy.

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