GABA-A RECEPTOR SUBTYPE MECHANISMS IN THE ABUSE-RELATED EFFECTS OF ALCOHOL

酒精滥用相关影响中的 GABA-A 受体亚型机制

• 批准号: 7958326
• 负责人: DONNA M PLATT
• 金额: $ 1.27万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-05-01 至 2010-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7958326
• 关键词: Alcohol abuse; Alcoholism; Computer Retrieval of Information on Scientific Projects Database; Funding; GABA-A Receptor; Grant; Institution; Medical; New England; Primates; Public Health; Relapse; Research; Research Personnel; Resources; Source; United States National Institutes of Health; alcohol effect; base; psychologic; receptor; social

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Alcoholism is a public health problem that is associated with debilitating medical, social, and psychological consequences. This project investigates specific GABAergic receptor mechanisms underlying the subjective, reinforcing, and relapse-inducing effects of alcohol and results will aid identification of receptor targets for the pharmacological management of alcohol abuse and relapse.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 酒精中毒是一个公共卫生问题，与衰弱的医疗，社会和心理后果有关。 本项目研究了特定的GABA能受体机制，这些机制是酒精的主观、强化和复发诱导作用的基础，结果将有助于确定酒精滥用和复发的药理学管理的受体靶点。