Natural History of AIDS Homosexual Men

请参阅说明)： 加州大学洛杉矶分校的网站作为Mac的临床网站，已经有25年的杰出表现， 维护1637名参与者中超过88.5%的当前状态信息。有同情心的人， 忠诚的工作人员，他们中的大多数人已经在研究中工作了15年以上(有些人已经25年了 几年)，被与会者认为是他们继续致力于加州大学洛杉矶分校Mac的关键。 实施了最先进的实验室程序，并实施了质量保证程序 地点。该中心招募了一批杰出的加州大学洛杉矶分校调查人员参与互委会， 并在各个科学领域发挥领导作用，领导52项研究出版物 自2003年以来，并为其他60篇Mac科学论文撰稿。 加州大学洛杉矶分校MACS临床中心的目标是： 1)维持1984-5年度征聘的男子和2002-3年度较新征聘的男子(主要是 拉美裔美国人和非洲裔美国人)； 2)收集男性特定的行为、临床和心理社会数据以及实验室标本； 3)处理实验室样本，用于地方和国家的血清、血浆和 细胞，并对这些来自洛杉矶的样本进行流式细胞术和血清学测量 参与者； 4)维护当地储存库，供当地调查人员使用； 5)对目前和未来的心血管并发症、肾功能、肝脏疾病、 MACS参与者的神经认知障碍、恶性肿瘤、衰老和基因组特征； 6)通过领导几个互委会工作组(核心)为互委会提供科学领导 实验室、恶性肿瘤/病理学、神经心理学)、质量控制程序的组织、 领导重要的互委会论文和参与其他论文，并积极参与双月刊 互委会的电话会议和会议； 7)招聘有经验的和新的调查人员，他们将带来新的科学见解和技能， 提高互委会科学的质量和广度。 相关性(请参阅说明)： 互委会将每六个月收集一次的信息和生物标本的大型数据库整合在一起 从1984年至2005年的6972名男性(主要是欧洲裔美国人)和2002年至2003年的男性(主要是拉丁裔和 非洲裔美国人)，并允许继续观察3243名幸存者。因此，互委会提供了一种 不可替代的资源，用于继续研究已治疗和未治疗的艾滋病毒感染和 艾滋病。

See instructions): The UCLA site has a 25-year history of outstanding performance as a clinical site of the MACS, maintaining current status information on over 88.5% of the 1637 participants. The empathetic, committed staff, most of whom have been with the study for more than 15 years (and some for 25 years), has been cited by participants as a key to their continued commitment to the UCLA MACS. State-of-the-art laboratory procedures have been implemented, and quality assurance procedures put in place. The Center has recruited an outstanding group of UCLA investigators to participate in the MACS, and to assume leadership roles in various scientific areas, taking leadership for 52 research publications since 2003 and contributing to 60 other MACS scientific papers. The objectives of the UCLA MACS Clinical Center are to: 1) Maintain the cohorts of men recruited in 1984-5 and the men more recently recruited in 2002-3 (primarily Hispanic-Americans and African-Americans); 2) Collect specific behavioral, clinical and psychosocial data, and laboratory specimens from the men; 3) Process laboratory specimens for the local and national specimen repositories of serum, plasma, and cells and to perform flow cytometry and serologic measurements on these samples from Los Angeles participants; 4) Maintain the local repository for use by local investigators; 5) Contribute to ongoing and future studies of cardiovascular complications, renal function, liver diseases, neurocognitive impairment, malignancies, aging, and genomic characteristics of MACS participants; 6) Contribute scientific leadership to the MACS through leadership of several MACS working groups (Core Laboratory, Malignancies/Pathology, Neuropsychology),organization of quality control procedures, leadership in key MACS papers and participation in others, and active participation in the bi-monthly conference calls and meetings of the MACS; 7) Recruit both experienced and new investigators who bring new scientific insights and skills that will enhance the quality and breadth of science in the MACS. RELEVANCE (Seeinstructions): The MACS incorporates a large database of information and biologic specimens collected every six months from 6,972 men followed since 1984-5 (primarily European-American) and 2002-3 (primarily Latino and Africa-American), and allows continuing observation of the 3243 survivors. Thus, the MACS provides an irreplaceable resourcefor continued study of the natural history of treated and untreated HIV infection and AIDS.