Bioinorganic Workshops in 2012 and 2014 and Bioinorganic Symposium in 2014

2012年和2014年生物无机研讨会和2014年生物无机研讨会

• 批准号: 8257434
• 负责人: CARSTEN KREBS
• 金额: $ 0.6万
• 依托单位: PENNSYLVANIA STATE UNIVERSITY, THE
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-04-01 至 2015-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8257434
• 关键词: American; Analytical Chemistry; Area; Belgium; Biochemistry; Bioinformatics; Bioinorganic Chemistry; Biological Sciences; Case Study; Cell physiology; Chemicals; Commit; Communities; Disease; Educational workshop; Event; Faculty; Functional disorder; Fund Raising; Genetic; Health; Human; International; Joints; Kinetics; Logistics; Methods; Molecular; Molecular Biology; Nature; Oxidation-Reduction; Participant; Pennsylvania; Physical Chemistry; Play; Postdoctoral Fellow; Protein Biochemistry; Reaction; Regulation; Request for Applications; Research; Research Infrastructure; Research Personnel; Role; Series; Societies; Spectrum Analysis; Students; Therapeutic; Training; Universities; Work; X-Ray Crystallography; abstracting; cofactor; frontier; graduate student; interdisciplinary approach; lectures; meetings; metalloenzyme; methionylmethionine; novel; posters; programs; research study; success; symposium

DESCRIPTION (provided by applicant): Bioinorganic chemistry is a vibrant field that encompasses a wide variety of scientific areas (e.g. genetics, molecular biology, biochemistry, bioinformatics, and analytical and physical chemistry) and an even wider assortment of methods to interrogate given questions (e.g. reaction kinetics, spectroscopy, X-ray crystallography, and computation). Because these areas are so diverse and require in-depth expertise, research in bioinorganic chemistry is most often carried out collaboratively. The exchange of ideas between bioinorganic researchers during scientific meetings and the training of graduate students and postdoctoral fellows in diverse methods used in this field play a particularly important role in bioinorganic chemistry. In this application we request support for such activities. In order to provide training to students and postdocs working in the area of bioinorganic chemistry, workshops were offered from 1985 to 2003 at the University of Louvain-la-Neuve, Belgium and from 1990 to 2000 at the University of Georgia (UGA). These workshops were offered to ~80 students and postdoctoral fellows and provided an unparalleled training opportunity. The workshop in Louvain-la-Neuve is now offered again, but no equivalent workshop is presently offered in the U.S.A. In 2010, the entire Bollinger/Krebs joint group hosted a short training workshop in bioinorganic chemistry for 36 students and postdoctoral fellows with diverse backgrounds (ranging from molecular biology, protein biochemistry to spectroscopy and computation). Because this workshop was very well received, we plan to offer workshop in 2012 and 2014 again. These will be significantly broader in scope (tentatively, participation of 12 faculty providing lectures and hands-on training in 14 subject areas). These workshops are aimed to provide this important training aspect in the U.S.A. again. The 2006 and 2010 summer symposia in Molecular Biology (hosted by the Department of Biochemistry and Molecular Biology at Penn State) were under the patronage of the bioinorganic group and entitled "Frontiers in Metallobiochemistry". These symposia were very successful in the bioinorganic community and the Penn State community. The bioinorganic group will also organize the 2014 "Frontiers in Metallobiochemistry" summer symposium and is committed to making this recurring (every four years) event an important meeting for the bioinorganic community. PUBLIC HEALTH RELEVANCE: Narrative: Research in the area of bioinorganic chemistry has many important implications to society, including human health, because metalloenzyme-catalyzed reactions are implicated in proper cellular functioning, while their dysfunction is often associated with the onset of severe diseases. Research in bioinorganic chemistry aims at unraveling these reactions and to exploit them for therapeutic purposes.

描述(申请人提供)：生物无机化学是一个充满活力的领域，它涵盖了广泛的科学领域(例如遗传学、分子生物学、生物化学、生物信息学以及分析和物理化学)，以及更广泛的询问特定问题的方法(例如反应动力学、光谱学、X射线结晶学和计算)。由于这些领域如此多样化，需要深入的专业知识，生物无机化学的研究大多是合作进行的。在生物无机化学领域，生物无机化学研究人员之间在科学会议期间的思想交流，以及对研究生和博士后研究员进行各种方法的培训，在生物无机化学中发挥着特别重要的作用。在此应用程序中，我们请求对此类活动提供支持。为了向从事生物无机化学领域工作的学生和博士后提供培训，1985年至2003年在比利时卢万-拉纽夫大学举办了讲习班，1990年至2000年在佐治亚大学举办了讲习班。这些讲习班为大约80名学生和博士后研究员提供了一个无与伦比的培训机会。2010年，整个Bollinger/Krebs联合小组为36名具有不同背景(从分子生物学、蛋白质生物化学到光谱学和计算)的学生和博士后举办了一个简短的生物无机化学培训研讨会。由于这次研讨会非常受欢迎，我们计划在2012年和2014年再次举办研讨会。这些活动的范围将大大扩大(暂定由12名教职员工参与，在14个学科领域提供讲座和实践培训)。这些研讨会的目的是再次在美国提供这一重要的培训方面。2006年和2010年夏季分子生物学专题讨论会(由宾夕法尼亚州立大学生物化学和分子生物学系主办)由生物无机小组赞助，题为“代谢生物化学前沿”。这些研讨会在生物无机界和宾夕法尼亚州立大学非常成功。生物无机组还将组织2014年“生物化学前沿”夏季研讨会，并致力于使这一重复性(每四年一次)活动成为生物无机界的重要会议。 公共卫生相关性：叙述：生物无机化学领域的研究对社会有许多重要的影响，包括人类健康，因为金属酶催化的反应与正常的细胞功能有关，而它们的功能障碍通常是 与严重疾病的发病有关。生物无机化学的研究旨在解开这些反应，并将其用于治疗目的。