Training Program in Endocrine and Diabetes Research

描述(申请人提供)：与内分泌有关的疾病；如糖尿病、代谢综合征、肥胖和骨质疏松症，已成为主要的公共卫生问题，因为它们的流行，它们的破坏性并发症(心脏病发作、中风、失明、截肢、透析)，以及它们对其他重大疾病的不利影响，如心血管、肾脏、神经、性腺和消化系统疾病。虽然管理和预防这些疾病已成为初级保健医生的任务，但内分泌科医生肩负着领导研究的重任，以更好地了解疾病过程并提供有效的预防和管理策略。这样一个崇高的目标需要有动力的内分泌学家，他们了解自己的领导角色，并致力于内分泌学、糖尿病和新陈代谢方面的研究和教育。然而，结合临床技能和研究专长的学术内分泌学家的数量正在减少。大多数内分泌奖学金项目培养的临床内分泌学家并不擅长内分泌研究，最终转到私人临床执业。这项申请的目的是利用韦恩州立大学医学院优越的学术环境和现有的ACGME内分泌学、糖尿病和新陈代谢临床培训计划，引导年轻的内分泌学家进入研究/学术轨道，并激励和培训他们在基础、临床和/或转化性内分泌研究学科，使他们能够发展成为成熟/全面的内分泌研究人员。这项建议涉及每年2名受训人员，他们是根据以前的学术成就和对生物医学内分泌研究的兴趣挑选出来的，他们在完成内分泌学、糖尿病和新陈代谢方面的临床研究后，将至少花两年时间进行研究培训。该计划将提供一种手段，发展和明确受训人员的研究技能，同时应成为过渡到他们成为独立研究资金和学术任命的竞争对手的桥梁机制，使他们可能成为未来内分泌研究的领导者。 公共卫生相关性：内分泌疾病，如糖尿病、肥胖症、代谢综合征和骨质疏松症的患病率正在增加，并具有毁灭性的并发症。该计划旨在招募、激励和培训年轻的内分泌学家成为学术内分泌学家，领导对内分泌相关疾病的更好理解和有效预防和管理策略的研究。

DESCRIPTION (provided by applicant): Endocrine-related illnesses; such as diabetes, metabolic syndrome, obesity and osteoporosis have become major public health concerns because of their prevalence, their devastating complication (heart attacks, stroke, blindness, amputations, dialysis) and their adverse effects on other major illnesses such as diseases of the cardiovascular, renal, nervous, gonadal and digestive systems. Whereas the management and the prevention of these diseases have become the mandate of primary care physicians, endocrinologists carry the burden of leading research to better understand the disease processes and provide effective prevention and management strategies. Such a noble goal requires motivated endocrinologists who understand their leadership role and who commit to research and education in endocrinology, diabetes and metabolism. However, the number of academic endocrinologists who combine clinical skills and research expertise is decreasing. Most endocrine fellowship programs produce clinical endocrinologists who are not skilled in endocrine investigation and eventually move to private clinical practice. The objective of this application is to take advantage of the excellent academic environment of the Wayne State University School of Medicine and of the existing ACGME clinical training program in endocrinology, diabetes and metabolism to direct young endocrinologists to the research/academic track, and motivate and train them in basic, clinical and/or translational endocrine research disciplines so they may develop into mature/rounded endocrine investigators. This proposal involves 2 trainees/year selected on the basis of prior scholarly achievement and interest in a career in biomedical endocrine investigation, who will spend a minimum of two years in research training after completing their clinical fellowship in endocrinology, diabetes and metabolism. This program shall provide a mean to develop and crystallize the investigative skills of the trainees and at the same time shall become a bridging mechanism for transitioning them to become competitive for independent research funds and academic appointment so they may become the future leaders of endocrine research. PUBLIC HEALTH RELEVANCE: Endocrine diseases, such as diabetes, obesity, metabolic syndrome and osteoporosis are Increasing in prevalence and have devastating complications. This program alms at recruiting, motivating and training young endocrinologists to become ACADEMIC ENDOCRINOLOGISTS leading research fpr a better understanding and effective prevention and management strategies of endocrine-related illnesses.