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Tier 2 Canada Research Chair in Ecotoxicogenomics and Endocrine Disruption

Tier 2 Canada Research Chair in Ecotoxicogenomics and Endocrine Disruption
加拿大二级生态毒基因组学和内分泌干扰研究主席
批准号:
CRC-2018-00320
负责人:
Langlois, Valérie
金额:
$7.29万
依托单位国家:
加拿大
项目类别:
Canada Research Chairs
财政年份:
2019
资助国家:
加拿大
项目状态:
已结题
起止时间:
2019-01-01 至 2020-12-31

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中文摘要
翻译
现有的和新出现的污染物继续产生并释放到海洋环境中。这些毒物与无脊椎动物的不良健康状况有关,包括死亡、发育迟缓、畸形、疾病和激素紊乱。本讲座的研究主题是在比较内分泌学和生态毒理学中采用最先进的方法来确定具有改变水生动物生理潜力的化学物质的分子和细胞效应。描述有毒物质的作用机制有助于加拿大风险评估人员和决策者更好地管理环境中污染物的命运和风险。
英文摘要
Existing and emerging pollutants continue to be produced and released into the aquaticenvironment. These toxicants have been associated with adverse health conditions invertebrates, including mortality, developmental delays, malformations, diseases, and hormonal disruption. The research theme of this Chair is to employ state-of-the-art methodology in comparative endocrinology and ecotoxicology towards determining the molecular and cellular effects of chemicals with increased potential for altering aquatic animal physiology. Characterizing the mechanisms of action of toxicants is assisting Canadas risk assessors and policy makers to better manage the fate and risk of contaminants in our environment.
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Genomic and Physiological Mechanisms of Androgen Signaling: Steroid 5-Reductase Knockout Investigation in Frogs
Genomic and Physiological Mechanisms of Androgen Signaling: Steroid 5-Reductase Knockout Investigation in Frogs
  • 批准号:
    RGPAS-2020-00037
  • 项目类别:
    Discovery Grants Program - Accelerator Supplements
  • 资助金额:
    $2.91万
  • 财政年份:
    2022
  • 负责人:
    Langlois, Valérie
  • 依托单位:
Tier 2 Canada Research Chair in Ecotoxicogenomics and Endocrine Disruption
Genomic and Physiological Mechanisms of Androgen Signaling: Steroid 5-Reductase Knockout Investigation in Frogs
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