Graduate Program in Cellular and Molecular Biology.

该提案要求在第32年之后继续提供资金，培养博士学位。纽约大学医学院细胞与分子生物学专业的候选人。该计划涉及五个基础科学部门以及化学的研究人员。培训内容包括大分子和亚细胞器的功能和生物发生的一般领域，以及调节细胞代谢、分化和生长以及发育过程中细胞间相互作用的机制。自上次更新申请以来，我们的教师增加了该计划在细胞和分子生物学前沿的几个新领域的强大代表性，包括细胞免疫学，转录生物学，化学生物学，细胞发病机制和疾病机制。 该计划的跨学科性质允许学生在接近研究项目和选择论文顾问时有广泛的视角。课程的设计为学员提供了一个先进的，但平衡的生物学教育，使他们能够理解和应用到他们的研究复杂的想法和生物化学，遗传学，免疫学和分子细胞生物学的方法。 医疗中心研究企业的知名度提高，新实验室空间的增加以及积极的全国性招聘计划使过去十年中有资格获得培训补助金支持的申请人数量增加了一倍多。 该计划包括讲座课程，辅导，研讨会和实验室研究，并要求在口头资格考试中取得令人满意的成绩。受训人员是从主要由本科生或那些最近毕业，但在一个研究领域就业的申请人池中选择。入学候选人由参与部门的教师委员会选出，他们的接受必须得到萨克勒研究所的批准，该研究所负责管理医学院基础医学科学的所有研究生课程。学生进入一个开放的程序，并选择他们的论文导师和研究领域在他们的第一年结束后，在不同的实验室完成三个学徒。个别委员会的教师遵循学员的进展，并指导他们在整个过程中的论文研究。要求提供资金，以支助30-40名受训人员中的5名受训人员。通常，获得博士学位需要四到五年的时间。℃下 学员准备进入对人类健康有影响的生物医学科学领域，了解细胞和分子生物学的基本机制，以及了解癌症，动脉粥样硬化和神经退行性疾病等病理过程。

This proposal requests funds to continue, beyond the 32nd year, a program for training Ph.D. candidates in Cellular and Molecular Biology at the New York University School of Medicine. This program involves investigators in five basic science departments as well as Chemistry. Training is offered in the general areas of function and biogenesis of macromolecules and subcellular organelles, as well as the mechanisms that regulate cell metabolism, differentiation and growth, and intercellular interactions during development. Additions to our faculty since the last renewal application add to this program strong representation in several new areas at the cutting edge of Cell and Molecular Biology, including Cellular Immunology, Transcriptional Biology, Chemical Biology, Cellular Pathogenesis, and Disease Mechanisms. The interdisciplinary character of the program allows for a wide perspective for the student in approaching a research project and selecting thesis advisors. The design of the curriculum provides trainees with an advanced, but balanced biological education that prepares them to understand and apply to their research sophisticated ideas and methodologies of biochemistry, genetics, immunology, and molecular cell biology. The increased visibility of the research enterprise at the Medical Center, the addition of new laboratory space as well as a vigorous nationwide recruitment program has more than doubled the number of applicants to the program who are eligible for training grant support in the past decade. The program consists of lecture courses, tutorials, seminars and laboratory research and requires satisfactory performance in an oral qualifying examination. Trainees are selected from an applicant pool which is composed primarily from undergraduates or those recently graduated but employed in a research field. Candidates for admission to are selected by a committee of faculty members of the participating departments and their acceptance must be approved by the Sackler Institute, which administers all graduate programs in the Basic Medical Sciences at the School of Medicine. Students enter an open program and choose their thesis advisors and areas of research at the end of their first year and after completing three apprenticeships in different laboratories. Individual committees of faculty members follow the progress of trainees and mentor them throughout the course of their thesis research. Funds are requested to support five trainees out of a total trainee group of 30-40. Normally, four to five years will be required to obtain the Ph.D. degree. Trainees are prepared to enter fields of the biomedical sciences that have an impact on human health with respect to understanding fundamental mechanisms of Cellular and Molecular Biology as well as understanding the pathological processes such as cancer, atherosclerosis, and neurodegenerative diseases.