Hispanics, built environment & metabolic syndrome

西班牙裔、建筑环境

• 批准号: 7580987
• 负责人: Jose Szapocznik
• 金额: $ 88.21万
• 依托单位: UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-03-15 至 2012-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7580987
• 关键词: Address; Affect; Age; Behavior; Behavioral; Biological; Biological Factors; Biology; Calories; Communities; Complex; County; Cuba; Devices; Diabetes Mellitus; Diet; Environment; Equation; Figs - dietary; Growth; Health; Hispanics; Immigrant; Individual; Inflammation; Insulin Resistance; Life Style; Longitudinal Studies; Measures; Mediating; Metabolic syndrome; Methodology; Modeling; Natural experiment; Nature; Neighborhoods; Obesity; Outcome; Outcome Study; Participant; Pathway interactions; Patient Self-Report; Physical activity; Population; Publishing; Radial; Relative (related person); Sampling; Selection Bias; Social Environment; Testing; Time; Weight Gain; age group; base; energy balance; meetings; prospective; residence

DESCRIPTION (provided by applicant): In a prospective longitudinal study, it is hypothesized that the built environment's walkability will impact the social environment's collective efficacy, and that these environmental variables together will influence physical activity. Controlling for diet, physical activity is hypothesized to predict adiposity, inflammation, and insulin resistance; and these in turn will predict progression in metabolic syndrome indicators. While these relationships have been tested separately, this application proposes an integrated and interdisciplinary test of the relationship among these variables. Hispanic immigrants are selected for this study because Hispanics have disproportionately high rates of diabetes. Moreover, for very recent immigrants, weight increases rapidly as a function of time in the US. The study proposes to explore trajectories of cultural change - and their impact on diet and physical activity - as a mechanism by which 'time in the US' may bring about its deleterious health outcome for this population. A sample is proposed that is uniquely suited to investigate this phenomenon in Hispanics, as well as the impact of the built environment on physical activity and health outcomes: Cuban immigrants within 90 days of arrival to the US. This sample addresses in part the self- selection bias that characterizes most built environment studies, because, when these individuals arrive in Miami-Dade County, they typically move to a neighborhood not of their choosing. Therefore, an ideal natural experiment occurs in which a naive sample in relation to non-walkable environments is distributed across a variety of walkability conditions. Participants will be 390, 30-45 year-old recent immigrants who do not meet criteria for metabolic syndrome. Built environment's walkability will be assessed through self-reports, and objectively using the .25 mile radius surrounding the participant's residence. Participants will be assessed on self-reported measures of collective efficacy, physical activity, diet, and biculturation, and objective measures of physical activity, adiposity, inflammation, insulin resistance, and metabolic syndrome indicators. Variables in the primary analyses will be continuously distributed. Growth curves will be estimated using growth curve methodology in a structural equations framework using Mplus 3.

描述（由申请人提供）：在一项前瞻性纵向研究中，假设建筑环境的步行性将影响社会环境的集体效能，并且这些环境变量共同将影响身体活动。假设控制饮食、体力活动可以预测肥胖、炎症和胰岛素抵抗；这些反过来将预测代谢综合征指标的进展。虽然这些关系已经被单独测试，但该应用程序提出了对这些变量之间关系的综合和跨学科测试。西班牙裔移民被选为这项研究的对象，因为西班牙裔的糖尿病发病率异常高。此外，对于新移民来说，体重随着在美国的时间的推移而迅速增加。该研究建议探索文化变迁的轨迹及其对饮食和身体活动的影响，作为“在美国的时间”可能给该人群带来有害健康结果的机制。提出了一个特别适合调查西班牙裔人这一现象以及建筑环境对身体活动和健康结果的影响的样本：抵达美国 90 天内的古巴移民。该样本部分解决了大多数建筑环境研究所特有的自我选择偏差，因为当这些人到达迈阿密戴德县时，他们通常会搬到不是他们选择的社区。因此，理想的自然实验发生，其中与不可步行环境相关的朴素样本分布在各种步行条件下。参与者将是 390 名 30-45 岁的新移民，不符合代谢综合征标准。建筑环境的步行适宜性将通过自我报告进行评估，并客观地使用参与者住所周围 0.25 英里的半径。参与者将接受自我报告的集体效能、体力活动、饮食和涵化的测量，以及体力活动、肥胖、炎症、胰岛素抵抗和代谢综合征指标的客观测量。初步分析中的变量将连续分布。将使用 Mplus 3 在结构方程框架中使用增长曲线方法来估计增长曲线。